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Modulation of GABA-Activated Currents in Rat Isolated Cerebellar Neurons by Lanthanum Ions

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Abstract

Lanthanum ions (10-1000 μM) potentiated GABA-activated currents and increased the sensitivity of GABAA receptors in isolated Purkinje cells from rat cerebellum. GABA receptors in Purkinje cells are comparable to receptors on other cells by their sensitivity lanthanum ions.

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REFERENCES

  1. S. N. Kolbaev, I. N. Sharonova, V. S. Vorobjev, and V. G. Skrebitskii, Byull. Eksp. Biol. Med., 127, No. 5, 539-542 (1999).

    Google Scholar 

  2. B. Barila, A. Cupello, and M. Robello, Neurosci. Lett., 298, No. 1, 13-16 (2001).

    Google Scholar 

  3. E. A. Barnard, P. Skolnick, and R. W. Olsen, Pharmacol. Rev., 50, No. 2, 291-313 (1998).

    Google Scholar 

  4. L. Chen, H. Wang, S. Vicini, and R. W. Olsen, Proc. Natl. Acad. Sci. USA, 97, No. 21, 11-557-11-562 (2001).

    Google Scholar 

  5. J. L. Fisher, J. Zhang, and R. L. Macdonald, Mol. Pharmacol., 52, No. 4 714-724 (1997).

    Google Scholar 

  6. J. Y. Ma and T. Narahashi, J. Neurosci., 13, No. 11, 4872-4879 (1993).

    Google Scholar 

  7. J. Y. Ma and T. Narahashi, Brain Res., 607, No. 1-2, 222-232

  8. W. Ma, P. A. Saunders, R. Somogyi, et al., J. Comp. Neurol., 338, No. 3, 337-359 (1993).

    Google Scholar 

  9. T. Narahashi, J. Y. Ma, O. Arakawa, et al., J. Cell. Mol. Neurobiol., 14, No. 6, 599-621 (1994).

    Google Scholar 

  10. T. R. Neelands and R. L. Macdonald, Mol. Pharmacol., 56, No. 3, 598-610 (1999).

    Google Scholar 

  11. D. B. Reichling and A. B. MacDermott, J. Physiol, 441, 199-218 (1991).

    Google Scholar 

  12. N. C. Saxena, T. R. Neelands, and R. L. Macdonald, Mol. Pharmacol., 51, No. 2, 328-335 (1997).

    Google Scholar 

  13. V. S. Vorobjev, J. Neurosci. Methods, 38, No. 2-3, 145-150 (1996).

    Google Scholar 

  14. V. S. Vorobjev, I. N. Sharonova, and H. L. Haas, Ibid., 68, No. 2, 303-307 (1996).

    Google Scholar 

  15. W. J. Zhu, J. F. Wang, L. Corsi, and S.Vicini, J. Physiol., 511, No. 3, 647-661 (1998).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Brain Research, Russian Academy of Medical Sciences, Moscow

    S. N. Kolbaev

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  1. S. N. Kolbaev
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Correspondence to S. N. Kolbaev.

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Kolbaev, S.N. Modulation of GABA-Activated Currents in Rat Isolated Cerebellar Neurons by Lanthanum Ions. Bulletin of Experimental Biology and Medicine 133, 44–47 (2002). https://doi.org/10.1023/A:1015100326377

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