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Reactions of cyclic enaminoketones with benzylidenemalononitriles. Synthesis of new fused heterocyclic systems containing the 1,4-dihydropyridine fragment

Abstract

The reactions of cyclic enaminoketones with benzylidenemalononitriles were examined and a new procedure was developed for the synthesis of fused heterocyclic systems containing the 1,4-dihydropyridine ring, viz., thienopyrimidoquinolines and furopyrimidoquinolines. The characteristic features of the reactions and the structures of the resulting compounds were investigated.

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Lichitsky, B.V., Ivanov, S.N., Dudinov, A.A. et al. Reactions of cyclic enaminoketones with benzylidenemalononitriles. Synthesis of new fused heterocyclic systems containing the 1,4-dihydropyridine fragment. Russian Chemical Bulletin 50, 2428–2432 (2001). https://doi.org/10.1023/A:1015056117968

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  • cyclic enaminoketones
  • benzylidenemalononitriles
  • fused 1,4-dihydropyridines
  • thienopyrimidoquinolines
  • furopyrimidoquinolines
  • Michael reaction