Abstract
The possibility of preparing 4-nitrobenzoic acid in a closed process cycle by oxidation of 4-nitrotoluene with an ozone-air mixture was examined. The optimal conditions of oxidation with multiple use of mother liquors were found, and the conditions for crystallization of 4-nitrobenzoic acid from the reaction mixture were determined. The effects of water, acetic anhydride, and catalyst on the oxidation performed in mother liquors after filtration of the target product were examined.
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Galstyan, A.G., Tyupalo, N.F., Patapenko, E.V. et al. Use of Ozone for Preparing 4-Nitrobenzoic Acid in a Closed Process Cycle. Russian Journal of Applied Chemistry 74, 1777–1779 (2001). https://doi.org/10.1023/A:1014802612863
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DOI: https://doi.org/10.1023/A:1014802612863