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Ultrastructure of the Rat Duodenal Endocrine Cells after Prolonged Irradiation

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Abstract

We propose classification of duodenal endocrine cells of intact rats based on ultrastructural signs of secretory granules and subdivided these cells into 10 basic types. The effect of long-term irradiation in a total dose of 2.5 Gy on ultrastructural organization of duodenal apudocytes was studied. Irradiation induced nonspecific changes of cell organelles in apudocytes. Differences in the ultrastructural disorganization were detected between different types of apudocyte populations and between different types of endocrine cells. Under conditions of adaptation to radiation apudocytes released the secretory product not only through molecular extrusion and exocytosis, but also via degranulation.

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REFERENCES

  1. L. I. Aruin, I. V. Zverkov, and V. A. Vinogradov, Klin. Med., No. 6, 22–31 (1987).

  2. E. N. Goncharenko and Yu. B. Kudryashov, Chemical Protection from Radiation Injury [in Russian], Moscow (1985), pp. 58–65.

  3. A. M. Kuzin, The Idea of Radiation Hormesis in the Atomic Era [in Russian], Moscow (1995), pp. 12–17.

  4. R. P. Manokhina, Regulatory Peptides and Biogenic Amines: Radiobiological and Oncoradiological Aspects [in Russian], Obninsk (1992), pp. 138–143.

  5. V. G. Ovakimov, G. M. Airapetyan, V. N. Ivanov, et al., Radiobiologiya, 10, No. 4, 561–565 (1970).

    Google Scholar 

  6. M. A. Osadchuk, V. F. Kirichuk, and I. M. Kvetnoi, Diffuse Neuroendocrine System: General Biological and Gastroenterological Aspects [in Russian], Saratov (1996), pp. 26–46.

  7. O. A. Smirnova, Radiobiologiya, 28, No. 6, 817–821 (1988).

    Google Scholar 

  8. A. M. Ugolev, Enterine (Intestinal Hormone) System [in Russian], Leningrad (1978), pp. 51–72.

  9. V. V. Yuzhakov, I. M. Kvetnoi, E. D. Ulitina, and V. P. Lepekhin, Regulatory Peptides and Biogenic Amines: Radiobiological and Oncoradiological Aspects [in Russian], Obninsk (1992), pp. 67–82.

  10. V. V. Yuzhakov, N. D. Yakovleva, I. M. Kvetnoi, and E. D. Ulitina, Med. Radiol., 39, No. 3, 39–45 (1994).

    Google Scholar 

  11. V. V. Yaglov and G. A. Lomonosov, Uspekhi Sovrem. Biol., No. 2, 264–276 (1985).

  12. H. Cheng and C. P. Leblond, Am. J. Anat., 141, 461 (1974).

    Google Scholar 

  13. T. Fujita, Igaku Shoin, Tokyo (1973).

  14. D. Grube, Anat. Embryol., 175, 151–162 (1986).

    Google Scholar 

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Authors and Affiliations

  1. Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk

    E. A. Odintsova, I. M. Kvetnoi, A. V. Trofimov, O. Yu. Tokarev & N. D. Yakovleva

  2. St. Petersburg Institute of Bioregulation and Gerontology, North-Western Division of, Russian Academy of Medical Sciences, Moscow

    E. A. Odintsova

Authors
  1. E. A. Odintsova
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  2. I. M. Kvetnoi
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  3. A. V. Trofimov
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  4. O. Yu. Tokarev
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  5. N. D. Yakovleva
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Odintsova, E.A., Kvetnoi, I.M., Trofimov, A.V. et al. Ultrastructure of the Rat Duodenal Endocrine Cells after Prolonged Irradiation. Bulletin of Experimental Biology and Medicine 132, 1207–1212 (2001). https://doi.org/10.1023/A:1014575702269

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