Abstract
In this paper we review the cost-effectiveness of HIV counseling and testing in various settings and populations in preventing the sexual transmission of human immunodeficiency virus, and we discuss how multiple and changing goals have influenced economic evaluations of these programs. The literature indicates that these interventions are generally cost-effective if targeted to groups of infected or high-risk individuals, although there is continuing debate over the efficacy of HIV counseling and testing in changing sexual behavior. For these reasons, HIV counseling and testing programs should be part of an overall prevention strategy which also includes more intensive sexual risk-reduction interventions such as individual, small-group, and community-level approaches.
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REFERENCES
Ades, A. E., Sculpher, M. J., Gibb, D. M., Gupta, R., and Ratcliffe, J. (1999). Cost effectiveness analysis of antenatal HIV screening in United Kingdom. British Medical Journal, 319, 1230-1234.
Altman, R., Shahied, S. I., Pizzuti, W., Brandon, D. N., Anderson, L., and Freund, C. (1992). Premarital HIV-1 testing in New Jersey. Journal of Acquired Immune Deficiency Syndromes, 5, 7-11.
Brandeau, M. L., Owens, D. K., Sox, C. H., and Wachter, R. M. (1993). Screening women of childbearing age for human immunodeficiency virus:Amodel-based policy analysis. Management Science, 39, 72-92.
Brandeau, M. L., and Owens, D. K. (1994). When women return to risk. Costs and benefits of HIV screening in the presence of relapse. In E.H. Kaplan and M. L. Brandeau (Eds.), Modeling the AIDS epidemic. Planning, policy, and prediction (pp. 121-136). New York: Raven Press.
Carpenter, C. C., Fischl, M. A., Hammer, S. M., Hirsch, M. S., Jacobsen, D. M., Katzenstein, D. A., et al. (1998). Antiretroviral therapy for HIV infection in 1998: Updated recommendations of the International AIDS Society-USA panel. Journal of the American Medical Association, 280, 78-86.
Centers for Disease Control. (1987). Public Health Service guidelines for counseling and antibody testing to prevent HIV infection and AIDS. Morbidity and MortalityWeekly Report, 36, 509-515.
Centers for Disease Control. (1990). Possible transmission of human immunodeficiency virus to a patient during an invasive dental procedure. Morbidity and Mortality Weekly Report, 39, 489-493.
Centers for Disease Control. (1991). Update: Transmission of HIV infection during an invasive dental procedure. Morbidity and Mortality Weekly Report, 40, 21-33.
Centers for Disease Control. (1992). Update: Investigation of patients who have been treated by HIV-infected health-care workers. Morbidity and MortalityWeekly Report, 41, 344-346.
Centers for Disease Control. (1994). HIV counseling, testing, and referral standards and guidelines. Atlanta: U.S. Department of Health and Human Services, Center for Disease Control.
Centers for Disease Control and Prevention. (1996). HIV counseling and testing in publicly funded sites: 1993-1994 summary report. Atlanta: Centers for Disease Control and Prevention.
Centers for Disease Control and Prevention. (1998a). HIV counseling and testing in publicly funded sites: 1996 annual report. Atlanta: U.S. Department of Health andHumanServices, Centers for Disease Control and Prevention.
Centers for Disease Control and Prevention. (1998b). Report of the NIH panel to define principles of therapy of HIV infection and guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. Morbidity and Mortality Weekly Report, 47, (No. RR-5).
Centers for Disease Control and Prevention. (2000). National HIV testing day at CDC-funded HIV counseling, testing, and referral sites-United States, 1994-1998. Morbidity and Mortality Weekly Report, 49, 529-532.
Cleary, P. D., Barry, M. J., Mayer, K. H., Brandt, A. M., Gostin, L., and Fineberg, H. V. (1987). Compulsory premarital screening for the human immunodeficiency virus. Journal of the American Medical Association, 258, 1757-1762.
Crobman, W. A., and Garcia, P. M. (1999). The cost-effectiveness of voluntary intrapartum rapidhumanimmunodeficiency virus testing for women without adequate prenatal care. American Journal of Obstetrics and Gynecology, 181, 1062-1071.
Ethier, K. A., Fox-Tierney, R., Nicholas, W. C., Salisbury, K. M., and Ickovics, J. R. (2000). Organizational predictors of prenatal HIV counseling and testing. American Journal of Public Health, 90, 1448-1452.
Farnham, P. G. (1998). Economic evaluation of HIV counseling and testing programs. The influence of program goals on evaluation. In D. R. Holtgrave (Ed.), Handbook of economic evaluation of HIV prevention programs (pp. 63-79). New York: Plenum.
Gail, M., Preston, D., and Piantadosi, S. (1989). Disease prevention models of voluntary confidential screening for human immunodeficiency virus (HIV). Statistics in Medicine, 8, 59-81.
Gelles, G. M. (1993). Costs and benefits of HIV-1 antibody testing of donated blood. Journal of Policy Analysis and Management, 12, 512-531.
Gibb, D. M., Ades, A. E., Gupta, R., and Sculpher, M. J. (1999). Costs and benefits to the mother of antenatal HIV testing: Estimates from simulation modelling. AIDS, 13, 1569-1576.
Gorsky R. D., Farnham, P. G., Straus W. L., Caldwell, B., Holtgrave, D. R., Simonds, R. J., et al. (1996). Preventing perinatal transmission of HIV-Costs and effectiveness of a recommended intervention. Public Health Reports, 111, 335-340.
Healton, C., Messeri, P., Abramson, D., Howard, J., Sorin, M. D., and Bayer, R. (1996). A balancing act: The tension between case-finding and primary prevention strategies in New York State's voluntary HIV counseling and testing program in women's health care setting. American Journal of Preventive Medicine, 12(Suppl. 1), 53-60.
Higgins, D. L., Galavotti, C., O'Reilly, K. R., Schnell, D. J., Moore, M., Rugg, D. L., et al. (1991). Evidence for the effects of HIV antibody counseling and testing on risk behaviors. Journal of the American Medical Association, 266, 2419-2429.
Holtgrave, D. R., Valdiserri, R. O., Gerber, A. R., and Hinman, A. R. (1993). Human immunodeficiency virus counseling, testing, referral, and partner notification services: A cost-benefit analysis. Archives of Internal Medicine, 153, 1225-1230.
Holtgrave, D. R., Valdiserri, R. O., and West, G. A. (1994). Quantitative economic evaluations of HIV-related prevention and treatment services: A review. Risk: Health, Safety and Environment, 5, 29-47.
Holtgrave, D. R., Qualls, N. L., Curran, J. W., Valdiserri, R. O., Guinan, M. E., and Parra, W. C. (1995). An overview of the effectiveness and efficiency of HIV prevention programs. Public Health Reports, 110, 134-146.
Holtgrave, D. R., Qualls, N. L., and Graham, J. D. (1996). Economic evaluation of HIV prevention programs. Annual Review of Public Health, 17, 467-488.
Immergluck, L. C., Cull, W. L., Schwartz, A., and Elstein, A. S. (2000). Cost-effectiveness of universal compared with voluntary screening for human immunodeficiency virus among pregnant women in Chicago. Pediatrics, 105, e54.
Kahn, J. G. (1996). The cost-effectiveness of HIV prevention targeting: How much bang for the buck? American Journal of Public Health, 86, 1709-1712.
Kahn, J. G., Washington, A. E., Showstack, J. A., Berlin, M., Phillips, K., and Watson, S. (1992). Updated Estimates of the Impact and Cost of HIV Prevention in Injection Drug Users. Report prepared for the Centers for Disease Control. San Francisco: Institute for Health Policy Studies, University of California.
Kamb, M. L., Fishbein, M. Douglas, J. M., Jr., Rhodes, F., Rogers, J., Bolan, G., et al. (1998). Efficacy of risk-reduction counseling to prevent human immunodeficiency virus and sexually transmitted diseases. A randomized controlled trial. Journal of the American Medical Association, 289, 1161-1167.
LaCroix, S. J., and Russo,G. (1996). A cost-benefit analysis of voluntary routine HIV-antibody testing for hospital patients. Social Science and Medicine, 42, 1259-1272.
Laupacis, A., Feeny, D., Detsky, A., and Tugwell, P. (1992). How attractive does a new technology have to be to warrant adoption and utilization? Tentative guidelines for using clinical and economic evaluations. Canadian Medical Association Journal, 146, 473-481.
Laupacis, A., Feeny, D., Detsky, A., and Tugwell, P. (1993). Tentative guidelines for using clinical and economic evaluations revisited. Canadian Medical Association Journal, 148, 927-929.
Mauskopf, J. A., Paul, J. E., Wichman, D. S., White, A. D., and Tilson, H. H. (1996). Economic impact of treatment of HIV-positive pregnant women and their newborns with zidovudine: Implications for HIV screening. Journal of the American Medical Association, 276, 132-138.
McKay, N. L., and Phillips, K. M. (1991). An economic evaluation of mandatory premarital testing for HIV. Inquiry, 28, 236-248.
Myers, E. R., Thompson, J. W., and Simpson, K. (1998). Cost-effectiveness of mandatory compared with voluntary screening for human immunodeficiency virus in pregnancy. Obstetrics and Gynecology, 91, 174-181.
Nakchbandi, I. A., Longenecker, C., Ricksecker, M. A., Latta, R. A., Healton, C., and Smith, D. G. (1998). A decision analysis of mandatory compared with voluntary HIV testing in pregnant women. Annals of Internal Medicine, 128, 760-767.
Owens, D. K., Harris, R. A., Scott, P. M., and Nease, R. F., Jr. (1995). Screening surgeons for HIV infection. A cost-effectiveness analysis. Annals of Internal Medicine, 122, 641-652.
Owens, D. K., Nease, R. F., Jr., and Harris, R. A. (1996). Costeffectiveness of HIV screening in acute care settings. Archives of Internal Medicine, 156, 394-404.
Petersen, L. R., White, C. R., and the Premarital Screening Study Group. (1990). Premarital screening for antibodies to human immunodeficiency virus type 1 in the United States. American Journal of Public Health, 80, 1087-1090.
Pinkerton, S. D., Johnson-Masotti, A. P., Holtgrave, D. R., and Farnham, P. G. (2002). A review of the cost-effectiveness of interventions to prevent sexual transmission of HIV in developed countries. AIDS and Behavior, 6, 15-31.
Postma, M. J., Beck, E. J., Mandalia, S., Sherr, L., Walters, M. D. S., Houweling, H., et al. (1999). Universal HIV screening of pregnant women in England: Cost effectiveness analysis. British Medical Journal, 318, 1656-1660.
Rugg, D. L., MacGowan, R. J., Stark, K. A., and Swanson, N. M. (1991). Evaluating the CDC program for HIV counseling and testing. Public Health Reports, 106, 708-713.
Stringer, J. S. A., and Rouse, D. J. (1999). Rapid testing and zidovudine treatment to prevent vertical transmission of human immunodeficiency virus in unregistered parturients: A cost-effectiveness analysis. Obstetrics and Gynecology, 94, 34-40.
Sweat, M., Gregorich, S., Sangiwa, G., Furlonge, C., Balmer, D., Kamenga, C., et al. (2000). Cost-effectiveness of voluntary HIV-1 counseling and testing in reducing sexual transmission of HIV-1 in Kenya and Tanzania. Lancet, 356, 113-121.
Turnock, B. J., and Kelly, C. J. (1989). Mandatory premarital testing for human immunodeficiency virus. The Illinois experience. Journal of the American Medical Association, 261, 3415-3418.
Valdiserri, R. O. (1997). HIV counseling and testing: Its evolving role in HIV prevention. AIDS Education and Prevention, 9(Suppl. B), 2-13.
Varghese, B., Peterman, T. A., and Holtgrave, D. R. (1999). Cost-effectiveness of counseling and testing and partner notification: A decision analysis. AIDS, 13, 1745-1751.
Voluntary HIV-1 Counseling and Testing Efficacy Study Group. (2000). Efficacy of voluntary HIV-1 counseling and testing in individuals and couples in Kenya, Tanzania, and Trinidad: A randomised trial. Lancet, 356, 103-112.
Weinhardt, L. S., Carey, M. P., Johnson, B. T., and Bickham, N. L. (1999). Effects of HIV counseling and testing on sexual risk behavior:Ameta-analytic review of published research, 1985-1997. American Journal of Public Health, 89, 1397-1405.
Weinstein, M. C., Graham, J. D., Siegel, J. E., and Fineberg, H. V. (1989). Cost-effectiveness analysis of AIDS prevention programs: Concepts, complications, and illustrations. In C. F. Turner, H. G. Miller, and L. E. Moses (Eds.), AIDS: Sexual behavior and intravenous drug use (pp. 471-499). Washington, DC: National Academy Press.
Wolitski, R. J., MacGowan, R. J., Higgins, D. L., and Jorgensen, C. M. (1997). The effects ofHIVcounseling and testing on riskrelated practices and help-seeking behavior. AIDS Education and Prevention, 9(Suppl. B), 52-67.
Wright-DeAguero, L. K., Gorsky, R. D., and Seeman, G. M. (1996). Cost of outreach for HIV prevention among drug users and youth at risk. Drugs and Society, 9, 185-197.
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Farnham, P.G., Pinkerton, S.D., Holtgrave, D.R. et al. Cost-Effectiveness of Counseling and Testing to Prevent Sexual Transmission of HIV in the United States. AIDS Behav 6, 33–43 (2002). https://doi.org/10.1023/A:1014524511777
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DOI: https://doi.org/10.1023/A:1014524511777