REFERENCES
A. A. Noyes and W. R. Whitney. Ñber die Auflösungsgeschwindigkeit von festen Stoffen in ihren eigenen Lösungen. Zeitschrift f. Physikal. Chemie 23:689–692 (1897).
W. Nernst and E. Brunner. Theorie der Reaktionsgeschwindigkeit in heterogenen Systemen. Zeitschrift f. Physik. Chemie 47:52–110 (1904).
V. G. Levich. Physicochemical Hydrodynamics, Engelwood Cliffs, Prentice Hall, New Jersey, 1962.
J. B. Dressman, G. L. Amidon, C. Reppas, and V. P. Shah. Dissolution testing as a prognostic tool for oral drug absorption-immediate release dosage forms. Pharm. Res. 15:11–22 (1998).
T. Bates, M. Gibaldi, and J. Kanig. Solubilizing properties of bile salt solutions I. J. Pharm. Sci. 55:191–199 (1966).
E. Nicolaides, E. Galia, C. Efthymiopoulos, J. B. Dressman, and C. Reppas. Forecasting the in vivo performance of four low solubility drugs from their in vitro dissolution data. Pharm. Res. 16: 1876–1882 (1999).
E. Galia, E. Nicolaides, D. Hörter, R. Löbenberg, C. Reppas, and J. B. Dressman. Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs. Pharm. Res. 15:698–705 (1998).
U. Klotz, H. Kroemer, and M. Schulz. Pantoprazole, der dritte Protonenpumpinhibitor. Pharm. Zeitung 32:24–32 (1995).
J. B. Dressman, R. R. Berardi, L. C. Dermentzoglou, T. L. Russell, S. P. Schmaltz, J. L. Barnett, and K. M. Jarvenpaa. Upper gastrointestinal (GI) pH in young, healthy men and women. Pharm. Res. 7:756–761 (1990).
L. Ovesen, F. Bentsen, U. Tage-Jentsen, N. T. Pedersen, B. R. Gram, and S. J. Rune. Intraluminal pH in the stomach, duodenum and proximal jejunum in normal subjects and patients with exocrine pancreatic insufficiency. Gastroenterology 90:958 (1986).
T. L. Russell, R. R. Berardi, J. L. Barnett, T. L. Osullivan, J. G. Wagner, and J. B. Dressman. pH-Related changes in the absorption of dipyridamole in the elderly. Pharm. Res. 11:136–143 (1994).
A. Melander. Influence of food on the bioavailability of drugs. Clin. Pharm. 3:337–351 (1978).
T. J. Mellinger and J.G. Bohorfoush. Blood levels of dipyridamole (Persantin®) in humans. Arch. Int. de Pharmacodyn. 163: 471–480 (1966).
S. D. Mithani. Dissolution and precipitation of dipyridamole: effect of pH and bile salt concentration, Doctoral Thesis, The University of Michigan, Ann Abor, Michigan, 1998.
B. Terhaag, F. Donath, G. Le Petit, and K. Feller. The absolute and relative bioavailability of dipyridamole from different preparations and the in vitro-in vivo comparison. Int. J. Clin. Pharmacol. Ther. Toxicol. 24:298–302 (1986).
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Kostewicz, E.S., Brauns, U., Becker, R. et al. Forecasting the Oral Absorption Behavior of Poorly Soluble Weak Bases Using Solubility and Dissolution Studies in Biorelevant Media. Pharm Res 19, 345–349 (2002). https://doi.org/10.1023/A:1014407421366
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DOI: https://doi.org/10.1023/A:1014407421366