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Optimization of Conditions of Preparative Chromatography of Carminomycin on a Carboxylic Cation Exchanger

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Abstract

The time course of equilibrium and nonequilibrium sorption of carminomycin on the carboxylic cation exchanger BDM-12 has been studied. Physicochemical requirements and the limits of the mobile phase flow rate are determined for the regular mode of preparative chromatography under the conditions of sharpening of the chromatographic zone.

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Authors and Affiliations

  1. Institute of High-Molecular-Weight Compounds of the Russian Academy of Sciences, St. Petersburg, 199004, Russia

    A. Yu. Toshchevikova & O. A. Pisarev

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  1. A. Yu. Toshchevikova
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  2. O. A. Pisarev
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Toshchevikova, A.Y., Pisarev, O.A. Optimization of Conditions of Preparative Chromatography of Carminomycin on a Carboxylic Cation Exchanger. Applied Biochemistry and Microbiology 38, 108–111 (2002). https://doi.org/10.1023/A:1014342028947

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  • DOI: https://doi.org/10.1023/A:1014342028947

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