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Adamantylazoles: IV. Acid-Catalyzed Adamantylation of Pyrazoles

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Abstract

Pyrazoles with pK B H + no more than 0.8 and having substituents in 3(5) position with effective van der Waals radii not exceeding 2 Å in a mixture of phosphoric and acetic acids at weight ratio 4:1 (H 0 -1,8) react with 1-adamantanol to afford the corresponding 1-(1-adamantyl)- or 1,4-di(1-adamantyl)pyrazoles.

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Authors and Affiliations

  1. St. Peresburg State Technological Institute, St. Petersburg, 198013, Russia

    A. S. Gavrilov, E. L. Golod, V. V. Kachala & B. I. Ugrak

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  1. A. S. Gavrilov
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  2. E. L. Golod
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  3. V. V. Kachala
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  4. B. I. Ugrak
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Gavrilov, A.S., Golod, E.L., Kachala, V.V. et al. Adamantylazoles: IV. Acid-Catalyzed Adamantylation of Pyrazoles. Russian Journal of Organic Chemistry 37, 1741–1746 (2001). https://doi.org/10.1023/A:1013930219704

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  • DOI: https://doi.org/10.1023/A:1013930219704

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