Abstract
We studied the influence of a low-energy He-Ne laser on the regeneration of the transected gastrocnemius muscle and state of the thymus and bone marrow in adult mongrel rats irradiated at 6 Gy using the histological, morphometric, and cytogenetic methods. The laser influence on both rat hind limbs (at total doses of 9.0–10.8 J/cm2) enhanced the regenerative capacity of the viradiated traumatized skeletal muscle, and reduced cytogenetic damage in the bone marrow and thymus cells. The changes in the thymus mass and histostructure suggest that the functional load on the thymus increased under studied the experimental conditions.
Similar content being viewed by others
REFERENCES
Akleev, A.V., On a Possible Cause of Immunodepression at Remote Timers after Irradiation, Tezisy dokladov Vsesoyuznogo soveshchaniya “Effektornye i regulyatornye funktsii immunnoi sistemy v obluchennom organizme” (Abstracts of Papers and the All-Union Conference “Effector and Regulatory Functions of the Immune System in the Irradiated Organism”), Radiobiologiya, 1990, vol. 30, no. 4, pp. 542-543.
Aleksandrov, M.T., Aref'ev, I.M., Bibikova, A.V., et al., Lasers in Medical Technology. Stimulating Effect of Laser Irradiation on Cell proliferation in Culture, Sredstva i metody kvantovoi elektroniki v meditsine (Means and Methods of Quantum Electronics in Medicine), Saratov: Saratov. Gos. Univ., 1976, p. 129.
Babaeva, A.G., Regeneratsiya i sistema immunogeneza (Regeneration and Immune System), Moscow: Meditsina, 1985.
Babaeva, A.G., Unity and Contrast of Cytogenetic Activity of Lymphocytes and Their Antibody-Forming Function during Restorative Processes in Organs, Byull. Eksperim. Biol. Med., 1999, vol. 128, no. 11, pp. 484-490.
Barilyak, I.R. and Lopushan, I.V., Cytogenetic Consequences of Helium-Neon Laser Irradiation I the Bone Marrow Cells of Rats, Patol. Fiziol. Eksperim. Terap., 1981, no. 3, pp. 50-53.
Barnes, D.W.H. and Khrushchov, N.G., Fibroblasts in Sterile Inflammation: Study in Mouse Radiation Chimeras, Nature, 1968, vol. 218, p. 599.
Bulyakova, N.V., Age-Related Dynamics of Antiradiation Resistance of Skeletal Muscle in Rats, Cand. Sci. (Biol.) Dissertation, Moscow, 1973.
Bulyakova, N.V., Influence of Helium-Neon Laser in Different Regimes of Irradiation on Corneal Cells after Ionizing Irradiation, Dokl. Akad. Nauk SSSR, 1984, vol. 279, no. 2, pp. 499-501.
Bulyakova, N.V. and Azarova, V.S., Influence of Total Gamma-Irradiation at Different Doses on the Structure of Rat Muscle Regenerates, Izv. Ross. Akad. Nauk. Ser. Biol., 2000, no. 4, pp. 413-421.
Bulyakova, N.V., Popova, M.F., Zubkova, S.M., et al., Stimulyatsiya regeneratsii obluchennykh i neobluchennykh skeletnykh myshts mlekopitayushchikh (lazernaya i tkanevaya terapiya) (Stimulation of Regeneration of Irradiated and Nonirradiated Skeletal Muscle: Laser and Tissue Therapy), Moscow: Nauka, 1995.
Bulyakova, N.V., Zubkova, S.M., Popova, M.F., et al., Effect of Pulse Infrared Laser Irradiation on Posttraumatic Regeneration of Locally Irradiated Skeletal Muscle and State of Thymus in Rats, Dokl. Ross. Akad. Nauk, 1996, vol. 349, no. 1, pp. 124-128.
Bulyakova, N.V., Zubkova, S.M., Azarova, V.S., et al., Regeneration of Irradiated Mechanically Damaged Skeletal Muscle in Rats after Infrared Laser Irradiation, Dokl. Ross. Akad. Nauk, 1998, vol. 359, no. 1, pp. 123-127.
Bulyakova, N.V., Zubkova, S.M., Azarova, V.S., et al., Regeneration of Gastrocnemius Muscle after Radiation and Mechanical Trauma and Long-Term Application of Pulse Infrared Laser Irradiation, Dokl. Ross. Akad. Nauk, 1999, vol. 364, no. 5, pp. 695-699.
Durmanov, K.A. and Akhmetov, M.M., Some Results of Application of Laser Rays in Therapy Radiation-Induced Ulcers, Materialy nauchnoi konferentsii po voprosam teoreticheskoi i klinicheskoi meditsiny (Materials of Scientific Conference on Problems of Theoretical and Clinical Medicine), Alma-Ata, 1973, vol. 6, pp. 533-535.
Inyushin, V.M., Karayanida, L.D., and Tkachenko, N.G., Comparative Estimate of Physiological Efficiency of Pulse and Continuous MKS (6300-6500 Å) and Role of Polarization, Svet gelii-neonovogo lazera v biologii i meditsine (Light of Helium-Neon Laser in Biology and Medicine), Alma-Ata, 1970, pp. 6-7.
Ivanov, A.A., Immunity and Nonspecific Factors of Protection in the Irradiated Organism, Tezisy dokladov Vsesoyuznogo soveshchaniya “Effektornye i regulyatornye funktsii immunnoi sistemy v obluchennom organizme” (Abstracts of Papers and the All-Union Conference “Effector and Regulatory Functions of the Immune System in the Irradiated Organism”), Radiobiologiya, 1990, vol. 30, no. 4, p. 530.
Kalinin, E.V., Reaction of Bone Marrow upon Damage of Eyes and Skin Cover by Direct and Reflected Irradiation of Helium-Xenon and Helium-Neon Gas Lasers, Gigiena Truda, 1979, no. 2, pp. 30-34.
Kapichnikova, L.G., Ugnivenko, V.I., and Vyal'ko, V.V., Effect of Monochromatic Red Light on Degenerative Changes of Muscle Tissue in the Limb Stump in Experiment, Tezisy Vsesoyuznoi konferentsii “Primenenie lazerov v klinike i eksperimente” (Abstracts of All-Union Conference “Application of Lasers in Clinic and Experiment”), Moscow, 1987, pp. 207-208.
Kharin, G.M., On the Influence of Helium-Neon Laser Irradiation on Histostructure of Lymphoid Organs, Lazer v travmatologii i ortopedii (Laser in Traumatology and Orthopedics), Leningrad: Nauka, 1979, pp. 18-24.
Khrushchov, N.G., Michurina, T.V., Vasil'eva, T.V., et al., Immunologicheskie aspekty biologii razvitiya (Immunological Aspects of Developmental Biology), Moscow: Nauka, 1984, pp. 166-189.
Kim, Yu.A., Treatment of Late Radiation-Induced Skin Ulcers by Laser Irradiation and Directed Bacterial Air Environment, Cand. Sci. (Med.) Dissertation, Obninsk: In-t Med. Radiol., 1987.
Kozlova, N.V., Effect of Ionizing Irradiation on Restorative Posttraumatic Processes in Skeletal Muscle Tissue after Single, Chronic, and Fractionated Irradiation, Cand. Sci. (Med.) Dissertation, Leningrad: San.-Gig. Med. In-t, 1961.
Michurina, T.V., Satdykova, G.V., Voskresenskii, D.K., et al., The Bone Marrow Origin of Cells Incapsulating a Foreign Body in Peritoneal Cavity of Xenogeneic Radiation Chimeras, Ontogenez, 1991, vol. 22, no. 1, pp. 76-83.
Moroz, V.A., Panov, A.V., and Bulgakov, A.K., Use of Helium-Neon Laser Irradiation in Preoperational Diapevtics of the Zone of Local Radiation-Induced Injury, Lazernaya i magnitnaya terapiya v eksperimental'nykh i klinicheskikh issledovaniyakh (Laser and Magnetic Therapy in Experimental and Clinical Studies), Obninsk, 1993, pp. 59-60.
Popova, M.F., Biological Analysis of Muscle Tissue Reaction to Radiation Damage under the Conditions of Mechanical Trauma, Dokl. Akad. Nauk SSSR, 1962, vol. 143, no. 2, pp. 444-447.
Popova, M.F., Plastic Protective-Restorative State of Regenerating Tissue, Doctoral (Biol.) Dissertation, Moscow: In-t Evol. Morfol. Ekol. Zhivot., 1976.
Popova, M.F., Radiochuvstvitel'nost' i stimuliruyushchie svoistva regeneriruyushchikh tkanei mlekopitayushchikh (Radiosensitivity and Stimulating Properties of Regenerating Mammalian Tissues), Moscow: Nauka, 1984.
Popova, M.F., Bulyakova, N.V., and Azarova, V.S., Use of Helium-Neon Laser for Stimulation of Regeneration of Radiation-Damaged Skeletal Muscle, Radiobiologiya, 1983, vol. 23, no. 1, pp. 50-53.
Poverennyi, A.M., Possible Causes of High Radiosensitivity of the Hemopoietic System, Tezisy dokladov Vsesoyuznogo soveshchaniya “Effektornye i regulyatornye funktsii immunnoi sistemy v obluchennom organizme” (Abstracts of Papers and the All-Union Conference “Effector and Regulatory Functions of the Immune System in the Irradiated Organism”), Radiobiologiya, 1990, vol. 30, no. 4, p. 538.
Shefer, G., Oron, U., and Halevy, O., Low-Energy Laser Irradiation: Mechanism of Action on Skeletal Muscle Satellite Cells, Abstr. Intern. Congress of Myology, Nice, France, 2000, p. 299.
Shukanova, N.A., Kazakevich, V.B., and Vorobei, A.V., Measurement of Receptor Properties of Thymocyte Membranes in Irradiated Animals, Tezisy dokladov Vsesoyuznogo soveshchaniya “Effektornye i regulyatornye funktsii immunnoi sistemy v obluchennom organizme” (Abstracts of Papers and the All-Union Conference “Effector and Regulatory Functions of the Immune System in the Irradiated Organism”), Radiobiologiya, 1990, vol. 30, no. 4, p. 533.
Tuzhilkova, T.N., Reaction of Muscle on Ioinizing Irradiation, Doctoral (Med.) Dissertation, Moscow: Akad. Med. Nauk SSSR, 1969.
Yarilin, A.A., Thymus and Influence of Irradiation on Immunity, Tezisy dokladov Vsesoyuznogo soveshchaniya “Effektornye i regulyatornye funktsii immunnoi sistemy v obluchennom organizme” (Abstracts of Papers and the All-Union Conference “Effector and Regulatory Functions of the Immune System in the Irradiated Organism”), Radiobiologiya, 1990, vol. 30, no. 4, pp. 530-531.
Zimonjic, D., Jankovic-Zagoricic, A., and Soldatovic, B., Changes in Mitotic Activity and Frequency of SCE in Laser Irradiated Cultures of Human Lymphocytes, Acta Veter.f (Beograd), 1985, vol. 35, nos. 1-2, pp. 33-40.
Zubkova, S.M., Bulyakova, N.V., Mikhailik, L.V., et al., Comparative Analysis of the Effect of Infrared Laser Irradiation and Ultrasound on Regeneration of Locally Irradiated Skeletal Muscle and State of Immune System in Rats, Vopr. Kurort. Fizioter. Lecheb. Fiz-ry, 1998, no. 6, pp. 11-16.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bulyakova, N.V., Azarova, V.S. Regeneration of Gastrocnemius Muscle and State of Immune System in γ-Irradiated Rats under the Influence of He-Ne Laser. Biology Bulletin 29, 31–42 (2002). https://doi.org/10.1023/A:1013285701221
Issue Date:
DOI: https://doi.org/10.1023/A:1013285701221