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Penetration of radionuclides across the skin: Glucans as possible inhibitors of metals permeation

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Abstract

Penetration of Cs+ , Cd 2+ and Co2+ions across an animal model of human skin (five-day-old rat skin) was studiedin vitro in vertical diffusion cells. Glucans (fibrilary beta-glucan, carboxymethyl-chitosan-glucan)were used as permeation inhibitors with the aim to reduce the potential toxicologicaleffect of these metals in humans. Of the glucans studied, carboxymethyl-chitosan-glucanwas the more effective inhibitor. The dose-dependency of this effect was demonstrated.

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Authors and Affiliations

  1. Faculty of Chemical Technology, Slovak University of Technology, Department of Environmental Technology, Radlinského 9, 842 27, Bratislava, Slovak Republic

    M. Harangozó

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  1. M. Harangozó
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Harangozó, M. Penetration of radionuclides across the skin: Glucans as possible inhibitors of metals permeation. Journal of Radioanalytical and Nuclear Chemistry 250, 189–191 (2001). https://doi.org/10.1023/A:1013272005838

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  • DOI: https://doi.org/10.1023/A:1013272005838

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