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Variations in trace element concentrations in breast milk with stages of lactation

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Abstract

The influence of stages of lactation on the mineral and trace elementconcentrations of breast milk collected from 20 healthy lactating women ina Nigeria population was investigated using instrumental neutron activationanalysis (INAA) and proton induced X-ray emission (PIXE) analysis. The breastmilk samples were divided into colostrum (day 1–5), transitional (day6–13) and mature milk (day 14–28). The result of the study showthat colostrum milk has a significantly higher mean concentration of Ca, Cl,Cu, Fe, Mg, Na and Zn than the transitional and mature milk. Furthermore,the mean concentrations of Fe, Mg, Na and Zn in transitional milk were foundto be significantly higher when compared with the mature milk. It was alsoobserved from the semi-log plot of the concentration of the elements againstdays of lactation that the concentration of all the elements decreased significantlythroughout the lactation period studied with Cu, Fe and Zn concentration showingthe greatest decline, particularly in the early stages of lactation.

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References

  1. F. Wang, F. Lai, J. Clin. Nutr., 101 (1971) 1201.

    Google Scholar 

  2. P. B. Mutch, L. S. Hurley, J. Clin. Nutr., 104 (1974) 828.

    Google Scholar 

  3. M. G. Karmakar, C. V. Ramakrishnan, Acta. Paediatr., 49 (1960) 599.

    Google Scholar 

  4. S. Munch-Petersen, Acta Paediatr., 39 (1951) 378.

    Google Scholar 

  5. E. Vuori, S. M. Makinen, R. Kara, P. Kuitunen, Am. J. Clin. Nutr., 33 (1980) 227.

    PubMed  Google Scholar 

  6. M. C. Neville, R. P. Keller, J. Seacat, C. E. Casey, J. C. Allen, P. Archer, Am. J. Clin. Nutr., 40 (1984) 635.

    PubMed  Google Scholar 

  7. R. M. Feeley, R. R. Eitenmiller, J. B. Jones, H. Barnhart, Am. J. Clin. Nutr., 37 (1983) 443.

    PubMed  Google Scholar 

  8. C. E. Casey, M. C. Neville, K. M. Hambidge, J. Clin. Nutr., 49 (1989) 773.

    Google Scholar 

  9. E. Rossipal, M. Krachler, Nutr. Res., 18 (1998) No. 1, 11.

    Google Scholar 

  10. F. A. Balogun, O. A. Akanle, J. A. Owa, N. M. Spyrou, Biol. Trace Elem. Res., 45 (1994) 471.

    Google Scholar 

  11. O. A. Akanle, F. A. Balogun, J. A. Owa, N. M. Spyrou, J. Radioanal. Nucl. Chem. 244 (2000) 231.

    Google Scholar 

  12. B. Hall, Am. J. Clin. Nutr., 32 (1979) 304.

    PubMed  Google Scholar 

  13. M. F. Picciano, Nutr. Rep. Int., 18 (1978) 5.

    Google Scholar 

  14. L. A. Vaughan, C. W. Weber, S. R. Kemberling, Am. J. Clin. Nutr., 32 (1979) 2301.

    PubMed  Google Scholar 

  15. B. Lonnerdal, L. R. Woodhouse, C. Glazier, J. Nutr., 117 (1987) 1385.

    PubMed  Google Scholar 

  16. E. Vuori, P. Kuitunen, Acta Paediatr. Scand., 68 (1979) 29.

    PubMed  Google Scholar 

  17. K. Rajalashmi, S. G. Srikantia, Am. J. Clin. Nutr., 33 (1980) 664.

    PubMed  Google Scholar 

  18. R. A. Mendelson, G. H. Anderson, M. H. Bryan, Early Hum. Develop., 6 (1982) 145.

    Google Scholar 

  19. N. F. Kreb, K. M. Hanbidge, M. A. Jacobs, J. O. Rasbach, Am. J. Clin. Nutr., 41 (1985) 560.

    PubMed  Google Scholar 

  20. A. Kirksey, J. A. Ernst, J. L. Roepke, Ta-Lei Tsai, Am. J. Clin. Nutr., 32 (1979) 30.

    PubMed  Google Scholar 

  21. B. Blanc, World Rev. Nutr. Diet., 36 (1981) 1.

    PubMed  Google Scholar 

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Spyrou, N.M. Variations in trace element concentrations in breast milk with stages of lactation. Journal of Radioanalytical and Nuclear Chemistry 249, 71–75 (2001). https://doi.org/10.1023/A:1013225507423

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