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A Prospective Study on Oocyte Survival Rate After ICSI: Influence of Injection Technique and Morphological Features

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Abstract

Purpose: To determine the influence of technical pitfalls and oocyte morphology on survival rate and cleavage behavior after ICSI.

Methods: A total of 2210 injection procedures was examined for morphological and technical deviations. Survival rate and cleavage behavior were evaluated.

Results: In 77.8% of all cases ICSI was unsuspicous. Out of 491 deviations from optimal injection deep penetration of the oocyte and abundant presence of cumulus cells showed significant correlation with degeneration rate (p < 0.001). Morphological anomalies associated with the periphery of the oocyte were rather related to degeneration than cytoplasmic anomalies (p < 0.001). Early embryonic development was not impaired by technical or morphological parameters.

Conclusions: To conclude, these prospective data may be of prognostic value in regard of the number of embryos available for transfer and may help to improve treatment outcome.

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Authors and Affiliations

  1. IVF-Unit, Women's General Hospital, Linz, Upper Austria, Austria

    Thomas Ebner, Cemil Yaman, Marianne Moser, Michael Sommergruber, Klaus Jesacher & Gernot Tews

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  1. Thomas Ebner
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  2. Cemil Yaman
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  3. Marianne Moser
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  4. Michael Sommergruber
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  5. Klaus Jesacher
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  6. Gernot Tews
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Ebner, T., Yaman, C., Moser, M. et al. A Prospective Study on Oocyte Survival Rate After ICSI: Influence of Injection Technique and Morphological Features. J Assist Reprod Genet 18, 623–628 (2001). https://doi.org/10.1023/A:1013171505702

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  • DOI: https://doi.org/10.1023/A:1013171505702

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