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Fluoro-containing Heterocycles: VI. New Derivatives of 1,3,4-Thiadiazino[6,5,4-i,j]quinoline

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Abstract

A series of new tricyclic fluoroquinolones was prepared by replacing fluorine atoms in derivatives of 2-R-8-Y-7-oxo-9,10-difluoro-7H-1,3,4-thiadiazino[6,5,4-i,j]quinoline-6-carboxylic acids. In acids and esters containing a hydrogen atom in position 8 occurred replacement of F10 by amine rests, and in compounds with a fluorine in position 8 was substituted either F8or F10 and F8depending on the amine character.

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Authors and Affiliations

  1. Ural State Technical University, Yekaterinburg, 620002, Russia

    E. V. Nosova, G. N. Lipunova, L. P. Sidorova & V. N. Charushin

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  1. E. V. Nosova
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  2. G. N. Lipunova
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  3. L. P. Sidorova
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  4. V. N. Charushin
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Nosova, E.V., Lipunova, G.N., Sidorova, L.P. et al. Fluoro-containing Heterocycles: VI. New Derivatives of 1,3,4-Thiadiazino[6,5,4-i,j]quinoline. Russian Journal of Organic Chemistry 37, 1169–1176 (2001). https://doi.org/10.1023/A:1013152700659

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