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Prenecrotic Contracture Damage in Cardiomyocytes: Photochemical Fluorochrome Staining and Fluorescent Microscopy of the Myocardium

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Abstract

Prenecrotic contracture changes in cardiomyocytes during ischemic and metabolic alteration of the myocardium are detected at the photooptic level by photochemical fluorochrome staining and examination in fluorescent light. Comparison of the fluorescent and polarization microscopic pictures of damaged cardiomyocytes showed relationships between optically active and isotropic constituents of the cell myofibrillar system. Contracture changes are determined by local mass redistribution in contractile compartments and transformations of the myofibril components, caused by protein structure coagulation in cardiomyocyte sarcomers.

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REFERENCES

  1. M. E. Evseeva, Byull. Eksp. Biol. Med., 130, No. 10, 378-381 (2000).

    Google Scholar 

  2. L. V. Kakturskii, Sudden Cardiac Death: Clinical Morphology[in Russian], Moscow (2000).

  3. V. K. Lazutin, N. N. Beskrovnaya, V. G. Popov, and A. S. Smetnev, Kardiologiya, No. 10, 35-39 (1979).

  4. L. M. Nepomnyashchikh, Byull. Eksp. Biol. Med., 121, No. 1, 4-13 (1996).

    Google Scholar 

  5. L. M. Nepomnyashchikh, Alterative Insufficiency of Cardiomyocytes in Metabolic and Ischemic Injuries[in Russian], Moscow (1998).

  6. L. M. Nepomnyashchikh, G. I. Nepomnyashchikh, E. L. Lushnikova, et al., Morphogenesis of The Most Significant General Pathological Processes in Human and Animal Organs and Tissues: 5 Scientific Discoveries in Biology and Medicine[in Russian], Moscow (1998).

  7. L. M. Nepomnyashchikh and V. G. Tsimmerman, Byull. Eksp. Biol. Med., 128, No. 9, 356-360 (1999).

    Google Scholar 

  8. Yu. G. Tsellarius, L. A. Semenova, and L. M. Nepomnyashchikh, Pathoanatomical Diagnosis of Prenecrotic Changes and Myocardial Infarction by Polarization Microscopy[in Russian], Moscow (1979).

  9. Yu. G. Tsellarius, L. A. Semenova, and L. M. Nepomnyashchikh, Arkh. Patol., No. 12, 3-13 (1980).

  10. Yu. G. Tsellarius, V. G. Tsimmerman, L. M. Nepomnyashchikh, and L. A. Semenova, Photochemical Fluorochrome Staining for Pathoanatomical Diagnosis of Prenecrotic Changes and Myocardial Infarction[in Russian], Moscow (1984).

  11. V. G. Tsimmerman, and Yu. G. Tsellarius, Arkh. Patol., No. 7, 72-74 (1976).

  12. I. D. Shperling, Arkh. Patol., No. 1, 24-29 (1981).

  13. B. N. Carle, Human Pathol., 12, No. 7, 643-647 (1981).

    Google Scholar 

  14. H. David, K.-F. Lindenau, J. Bohm, et al., Exp. Pathol. (Jena), 14, No. 3-4, 141-156 (1977).

    Google Scholar 

  15. R. B. Jennings, Arch. Inst. Cardiol. Mex., 34-35, Suppl. 3, 156-172 (1980).

    Google Scholar 

  16. Z. Matejkova, A. Bozner, J. Dostal, and K. Boda, Cesk. Patol., 29, No. 2, 61-63 (1993).

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology and Pathomorphology, Institute of Regional Pathology and Pathomorphology, Siberian Division of Russian Academy of Medical Sciences, Institute of Cytology and Genetics, Siberian Division of, Russian Academy of Sciences, Novosibirsk

    L. M. Nepomnyashchikh & V. G. Zimmermann

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  1. L. M. Nepomnyashchikh
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  2. V. G. Zimmermann
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Nepomnyashchikh, L.M., Zimmermann, V.G. Prenecrotic Contracture Damage in Cardiomyocytes: Photochemical Fluorochrome Staining and Fluorescent Microscopy of the Myocardium. Bulletin of Experimental Biology and Medicine 132, 907–913 (2001). https://doi.org/10.1023/A:1013147524226

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  • DOI: https://doi.org/10.1023/A:1013147524226

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