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Construction of comparative cytogenetic maps of the Chinese hamster to mouse, rat and human

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Abstract

We constructed comparative cytogenetic maps of the Chinese hamster to mouse, rat and human by fluorescence in-situ hybridization using 36 cDNA clones of mouse, rat, Syrian hamster, Chinese hamster and human functional genes. In this study, 30 out of the 36 genes were newly mapped to Chinese hamster chromosomes. The chromosomal homology of the Chinese hamster was identified and arranged in 19, 19 and 18 segments of conserved synteny in mouse, rat and human, respectively. Additionally, two of the 19 segments homologous to mouse chromosomes were initially identified in this study.

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Authors and Affiliations

  1. Laboratory of Cytogenetics, Division of Bioscience, Graduate School of Environmental Earth Science, Hokkaido University, North 10, West 8, Kita-ku, Sapporo, 060-0810, Japan

    Asato Kuroiwa, Kazumi Matsubara & Yoichi Matsuda

  2. Laboratory of Animal Genetics, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan

    Asato Kuroiwa & Takao Namikawa

  3. Experimental Animal Center, Miyazaki Medical College, 5200 Kihara, Kiyotake-cho, Miyazaki, 889-1601, Japan

    Kimiyuki Tsuchiya

  4. Chromosome Research Unit, Faculty of Science, Hokkaido University, North 10, West 8, Kita-ku, Sapporo, 060-0810, Japan

    Yoichi Matsuda

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  1. Asato Kuroiwa
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  2. Kimiyuki Tsuchiya
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  3. Kazumi Matsubara
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  4. Takao Namikawa
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  5. Yoichi Matsuda
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Kuroiwa, A., Tsuchiya, K., Matsubara, K. et al. Construction of comparative cytogenetic maps of the Chinese hamster to mouse, rat and human. Chromosome Res 9, 641–648 (2001). https://doi.org/10.1023/A:1012952223509

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