References
McDonald KM, Mock J, D'Aloia A, et al. Bradykinin antagonism inhibits the antigrowth effect of converting enzyme inhibition in the dog myocardium after discrete transmural myocardial necrosis. Circulation 1995; 91: 2043-2048.
Schieffer B, Wirger A, Meybrunn M, et al. Comparative effects of chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on cardiac remodelling after myocardial infarction in the rat. Circulation 1994; 89: 2273-2282.
Greenberg B, Quinones MA, Koilpillai C, et al. Effects of long-term enalapril therapy on cardiac structure and function in patients with left ventricular dysfunction. Results of theSOLVDechocardiography substudy. Circulation 1995; 91: 2573-2581.
Doughty R, Whalley G, MacMahon S, et al. Carvedilol reduces left ventricular volumes in patients with heart failure of ischemic origin. J Am Coll Cardiol 1994; 24: 1762-1768.
Groenning BA, Nillson JC, Sondergaard L, Fritz-Hansen T, Larsson HBW, Hildebrandt PR. Antiremodeling effects in the left ventricle during beta-blockade with metoprolol in the treatment of chronic heart failure. J Am Coll Cardiol 2000; 36: 2072-2080.
Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT. Remodelling of the rat right and left ventricle in experimental hypertension. Circ Res 1990; 67: 1355-1364.
Sivestre JS, Heymes C, Oubenaissa A, et al. Activation of cardiac aldosterone production in rat myocardial infarction. Circulation 1999; 99: 2694-2701.
Di Pasquale P, Cannizzarro S, Scandurra A, Giubilato A, Scalzo S, Paterna S. ACE-inhibition plus mineralocorticoid antagonism versus ACE-inhibition alone in patients with anterior myocardial infarction. Cardiovasc Drugs Ther 2001; 15: 309-314.
Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999; 341: 709-717.
Pitt B, Williams G, Remme W, et al. The EPHESUS trial: Eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Cardiovasc Drugs Ther 2001; 15: 79-87.
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Remme, W.J. Aldosterone and Myocardial Infarction—Are Aldosterone Antagonists Needed to Prevent Remodelling or Does Ace Inhibition Suffice?. Cardiovasc Drugs Ther 15, 297–298 (2001). https://doi.org/10.1023/A:1012746312309
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DOI: https://doi.org/10.1023/A:1012746312309