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Effects of Peptides on Generation of Reactive Oxygen Species in Subcellular Fractions of Drosophila Melanogaster

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Abstract

We studied the effects of Epithalon (Ala-Glu-Asp-Gly) and Vilon (Lys-Glu) on free radical processes in highly inbred HA+line of Drosophila melanogaster. Vilon inhibited generation of reactive oxygen species in mitochondria, but stimulated this process in the cytosol. We found sex- and age-related differences in the generation of reactive oxygen species and cytosol antioxidant activity.

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Authors and Affiliations

  1. St. Petersburg Institute of Bioregulation and Gerontology, Northwestern Division of the Russian Academy of Medical Sciences, Russia

    V. Kh. Khavinson, S. V. Myl'nikov, T. I. Oparina & A. V. Arutyunyan

  2. Department of Genetics and Selection, St. Petersburg State University, Russia

    V. Kh. Khavinson, S. V. Myl'nikov, T. I. Oparina & A. V. Arutyunyan

  3. D. O. Ott Institute of Obstetrics and Gynecology, Russian Academy of Medical Sciences, St. Petersburg

    V. Kh. Khavinson, S. V. Myl'nikov, T. I. Oparina & A. V. Arutyunyan

Authors
  1. V. Kh. Khavinson
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  2. S. V. Myl'nikov
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  3. T. I. Oparina
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  4. A. V. Arutyunyan
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Khavinson, V.K., Myl'nikov, S.V., Oparina, T.I. et al. Effects of Peptides on Generation of Reactive Oxygen Species in Subcellular Fractions of Drosophila Melanogaster. Bulletin of Experimental Biology and Medicine 132, 682–685 (2001). https://doi.org/10.1023/A:1012588530643

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  • DOI: https://doi.org/10.1023/A:1012588530643

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