Abstract
The MspI restriction polymorphism of the serotonin 2A receptor gene (5HT2A) was typed in populations of the Volga–Ural region (Bashkirs, Chuvashes, Tatars, Udmurts, Maris, Mordovians, Komis, and Russians inhabiting the Republic of Bashkortostan). Population-specific patterns of the main polymorphism indices distribution were established. Specific trends in the changes of genotype and allele frequency of the 5HT2Agene depending on the ethnicity of the population were revealed.
Similar content being viewed by others
REFERENCES
Popova, N.K., A Role of Brain Mediators in Inherited Behavioral Changes Resulting from Domestication, in Sovremennye kontseptsii evolyutsionnoi genetiki: Sbornik nauchykh trudov (Modern Concepts in Evolutionary Genetics: Collection of Works), Novosibirsk: Nauka, 2000, pp. 319-326.
Shabanov, P.D. and Kalishevich, S.Yu., Biologiya algokolizma (Biology of Alcoholism), St. Petersburg: Lan', 1998.
Kaplan, G.I. and Sedok, B.J., Klinicheskaya psikhiatriya (Clinical Psychiatry), Moscow: Meditsyna, 1994, vol. 1.
Pyatnitskaya, I.N., Narkomanii: Rukovodstvo dlya vrachei (Narcomanias: A Handbook for Physicians), Moscow: Meditsyna, 1994.
Galeeva, A.R., Yur'ev, E.B., and Khusnutdinova, E.K., Study of the Polymorphism of the Serotonin Transporter Gene in Populations of the Volga–Ural Region, Genetika (Moscow), 1999, vol. 35, no. 9, pp. 1302-1304.
Galeeva, A.R., Yur'ev, E.B., and Khusnutdinova, E.K., Polymorphism of the Dopamine Receptor D2 Gene in Populations of the Volga–Ural Region, Genetika (Moscow), 2000, vol. 36, no. 10, pp. 1394-1400.
Collier, D.A., Arranz, M.J., Li, T., et al., Association between 5HT2A Gene Promoter Polymorphism and Anorexia Nervosa, Lancet, 1997, vol. 350, p. 412.
Sorbi, S., Nacmias, B., Tedde, A., et al., 5HT2A Promoter Polymorphism in Anorexia Nervosa, Lancet, 1998, vol. 351, p. 1785.
Warren, J.T., Peacock, M.L., Rodrigues, L.C., and Fink, J.L., An Msp I Polymorphism in the Human Serotonin Receptor Gene ( HTR2 ): Detection by DGGE and RFLP Analysis, Hum. Mol. Genet., 1993, vol. 2, p. 338.
Nakamura, T., Matsushita, S., Nishiguchi, N., et al., Association of a Polymorphism of the 5HT2A Receptor Gene Promoter Region with Alcohol Dependence, Mol. Psychiatry, 1999, vol. 4, no. 1, pp. 85-89.
Roff, D.A. and Bentzen, P., The Statistical Analysis of Mitochondrial DNA: x2 and the Problem of Small Samples, Mol. Biol. Evol., 1989, vol. 6, pp. 539-545.
Enoch, M.-A., Goldman, D., Barnett, R., et al., Association between Seasonal Affective Disorder and the 5HT2A Promoter Polymorphism,–1438G/A, Mol. Psychiatry, 1999, vol. 4, no. 1, pp. 89-92.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Galeyeva, A.R., Jur'ev, E.B. & Khusnutdinova, E.K. Polymorphism of the Serotonin 2A Receptor Gene in Populations of the Volga–Ural Region. Russian Journal of Genetics 37, 1332–1334 (2001). https://doi.org/10.1023/A:1012525629445
Issue Date:
DOI: https://doi.org/10.1023/A:1012525629445