Skip to main content
Log in

Polymorphism of the Serotonin 2A Receptor Gene in Populations of the Volga–Ural Region

  • Published:
Russian Journal of Genetics Aims and scope Submit manuscript

Abstract

The MspI restriction polymorphism of the serotonin 2A receptor gene (5HT2A) was typed in populations of the Volga–Ural region (Bashkirs, Chuvashes, Tatars, Udmurts, Maris, Mordovians, Komis, and Russians inhabiting the Republic of Bashkortostan). Population-specific patterns of the main polymorphism indices distribution were established. Specific trends in the changes of genotype and allele frequency of the 5HT2Agene depending on the ethnicity of the population were revealed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. Popova, N.K., A Role of Brain Mediators in Inherited Behavioral Changes Resulting from Domestication, in Sovremennye kontseptsii evolyutsionnoi genetiki: Sbornik nauchykh trudov (Modern Concepts in Evolutionary Genetics: Collection of Works), Novosibirsk: Nauka, 2000, pp. 319-326.

    Google Scholar 

  2. Shabanov, P.D. and Kalishevich, S.Yu., Biologiya algokolizma (Biology of Alcoholism), St. Petersburg: Lan', 1998.

    Google Scholar 

  3. Kaplan, G.I. and Sedok, B.J., Klinicheskaya psikhiatriya (Clinical Psychiatry), Moscow: Meditsyna, 1994, vol. 1.

    Google Scholar 

  4. Pyatnitskaya, I.N., Narkomanii: Rukovodstvo dlya vrachei (Narcomanias: A Handbook for Physicians), Moscow: Meditsyna, 1994.

    Google Scholar 

  5. Galeeva, A.R., Yur'ev, E.B., and Khusnutdinova, E.K., Study of the Polymorphism of the Serotonin Transporter Gene in Populations of the Volga–Ural Region, Genetika (Moscow), 1999, vol. 35, no. 9, pp. 1302-1304.

  6. Galeeva, A.R., Yur'ev, E.B., and Khusnutdinova, E.K., Polymorphism of the Dopamine Receptor D2 Gene in Populations of the Volga–Ural Region, Genetika (Moscow), 2000, vol. 36, no. 10, pp. 1394-1400.

    Google Scholar 

  7. Collier, D.A., Arranz, M.J., Li, T., et al., Association between 5HT2A Gene Promoter Polymorphism and Anorexia Nervosa, Lancet, 1997, vol. 350, p. 412.

    Google Scholar 

  8. Sorbi, S., Nacmias, B., Tedde, A., et al., 5HT2A Promoter Polymorphism in Anorexia Nervosa, Lancet, 1998, vol. 351, p. 1785.

    Google Scholar 

  9. Warren, J.T., Peacock, M.L., Rodrigues, L.C., and Fink, J.L., An Msp I Polymorphism in the Human Serotonin Receptor Gene ( HTR2 ): Detection by DGGE and RFLP Analysis, Hum. Mol. Genet., 1993, vol. 2, p. 338.

    Google Scholar 

  10. Nakamura, T., Matsushita, S., Nishiguchi, N., et al., Association of a Polymorphism of the 5HT2A Receptor Gene Promoter Region with Alcohol Dependence, Mol. Psychiatry, 1999, vol. 4, no. 1, pp. 85-89.

    Google Scholar 

  11. Roff, D.A. and Bentzen, P., The Statistical Analysis of Mitochondrial DNA: x2 and the Problem of Small Samples, Mol. Biol. Evol., 1989, vol. 6, pp. 539-545.

    Google Scholar 

  12. Enoch, M.-A., Goldman, D., Barnett, R., et al., Association between Seasonal Affective Disorder and the 5HT2A Promoter Polymorphism,–1438G/A, Mol. Psychiatry, 1999, vol. 4, no. 1, pp. 89-92.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Galeyeva, A.R., Jur'ev, E.B. & Khusnutdinova, E.K. Polymorphism of the Serotonin 2A Receptor Gene in Populations of the Volga–Ural Region. Russian Journal of Genetics 37, 1332–1334 (2001). https://doi.org/10.1023/A:1012525629445

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1012525629445

Keywords

Navigation