Abstract
Intranasal administration of Semax, peptide Pro-Gly-Pro, and a mixture of peptides Pro-Gly+Gly-Pro to rats for 5 days enhanced anticoagulant and fibrinolytic potential of the plasma (total fibrinolytic activity and plasmin and plasminogen activator activities) and decreased antiplasmin concentration. Semax and Pro-Gly-Pro decreased the weight of thrombi during experimental thrombosis.
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Cherkasova, K.A., Lyapina, L.A. & Ashmarin, I.P. Comparative Study of Modulatory Effects of Semax and Primary Proline-Containing Peptides on Hemostatic Reactions. Bulletin of Experimental Biology and Medicine 132, 625–626 (2001). https://doi.org/10.1023/A:1012503606536
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DOI: https://doi.org/10.1023/A:1012503606536