Abstract
The protolytic properties of 2,8,14,20-tetramethyl-5,11,17,23-tetrakis(N-morpholino)methylcalix[4]resorcinolarene were studied by pH-potentiometric titration. Its crystal and molecular structure was determined by single crystal X-ray diffraction and UV spectroscopy. In solution the macrocycle exists as a zwitter-ion. In the crystal, the calixresorcinolarene molecule is in the cone conformation; two pairs of the opposite morpholine substituents are oriented inside and outside the macrocycle cavity and therefore show different acid properties.
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Morozova, Y.E., Gubaidullin, A.T., Kazakova, E.K. et al. Protolytic Properties and Molecular Structure of 2,8,14,20-Tetramethyl-5,11,17,23-tetrakis(N-morpholino)- methylcalix[4]resorcinolarene. Russian Journal of General Chemistry 71, 119–125 (2001). https://doi.org/10.1023/A:1012350010806
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DOI: https://doi.org/10.1023/A:1012350010806