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Synthesis and Reductive Transformations of 11-Deoxyprostanoids with a 4,5,6,6a-Tetrahydro-3aH-cyclopenta[d]isoxazole Fragment in the ω-Chain

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Abstract

A new prostanoid precursor with a 4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole fragment in the ω-chain was synthesized using the nitrile oxide technique. Its reduction afforded new 11-deoxyprostanoids with modified α- and ω-chains.

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Authors and Affiliations

  1. National Academy of Sciences of Belarus, Institute of Bioorganic Chemistry, ul. Akademika Kuprevicha 5/2, Minsk, 220141, Belarus

    E. V. Koroleva, Ya. M. Katok & F. A. Lakhvich

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  1. E. V. Koroleva
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  2. Ya. M. Katok
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  3. F. A. Lakhvich
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Koroleva, E.V., Katok, Y.M. & Lakhvich, F.A. Synthesis and Reductive Transformations of 11-Deoxyprostanoids with a 4,5,6,6a-Tetrahydro-3aH-cyclopenta[d]isoxazole Fragment in the ω-Chain. Russian Journal of Organic Chemistry 37, 29–33 (2001). https://doi.org/10.1023/A:1012309013765

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  • DOI: https://doi.org/10.1023/A:1012309013765

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