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Selection of a potential probiotic Lactobacillus strain and subsequent in vivo studies

Antonie van Leeuwenhoek volume 80, pages 193–199 (2001)Cite this article

Abstract

The probiotic potential of a Lactobacillus strain, isolated from pig faeces, was assessed as a probiotic in piglets. The strain was examined for resistance to pH 2.0, 0.5% oxgall and antibiotics, and antimicrobial activities against enteric pathogenic bacteria. The probiotic strain, L. reuteri BSA131, was administered through the feed to 25 1-month-old Landrace piglets. The piglets were divided into five groups of five piglets each and fed with different diets for 28 days. The daily consumption of L. reuteriBSA131 was assigned into two groups by the concentration of 106 or 108 freeze-dried bacteria. Fecal samples were collected before, during, and after consumption. Lactobacilli and enterobacteria cell counts were determined in the fecal samples. The liveweight gains and feed consumption of the piglets were recorded daily. This study showed that strain BSA 131 enhanced liveweight gains and feed conversion rates in piglets. It also showed a significant increase in lactobacilli cell counts and decreases in enterobacterial numbers in the fecal samples. Strain BSA 131 was considered to be a potential probiotic for piglets, especially after weaning.

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Authors and Affiliations

  1. Korean Collection for Type Cultures, Korea Research Institute of Bioscience and Biotechnology, Yusung, P.O. Box 115, Taejon, 305-600, South Korea

    Young-Hyo Chang, Hong-Joong Kim & Yong-Ha Park

  2. Graduate School of Biotechnology, Korea University, Seoul, 136-701, South Korea

    Young-Hyo Chang & Young-Bae Kim

  3. Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, 567-0047, Japan

    Jong-Keun Kim

  4. Deparment of Microbiology, College of Medicine, Chung-Ang University, Seoul, 156–756, South Korea

    Won-Yong Kim

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  1. Young-Hyo Chang
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  2. Jong-Keun Kim
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  3. Hong-Joong Kim
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  4. Won-Yong Kim
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  5. Young-Bae Kim
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  6. Yong-Ha Park
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Correspondence to Young-Hyo Chang.

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Chang, YH., Kim, JK., Kim, HJ. et al. Selection of a potential probiotic Lactobacillus strain and subsequent in vivo studies. Antonie Van Leeuwenhoek 80, 193–199 (2001). https://doi.org/10.1023/A:1012213728917

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  • DOI: https://doi.org/10.1023/A:1012213728917

  • antibiotics
  • antimicrobial
  • feed trial
  • intestinal microflora
  • Lactobacillus
  • probiotics