Abstract
Long-term cytogenetic monitoring was carried out in adolescents of the town of Kemerovo. In total, aberrant metaphase frequency increased from 1.53% in 1992 to 4.40% in 1996 in Kemerovo adolescents, being significantly higher than a control frequency from 1993 to 1996. In all samples, chromosome aberrations mostly included acentric fragments, while exchanges were rare. The highest number of aberrations per aberrant metaphase was 2 in Kemerovo adolescents and 1 in the control sample. The observed increase in total number of chromosome aberrations suggests that the mutagenic effect of chemical environmental pollutants on Kemerovo adolescents increased over the five years.
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Volkov, A.N., Druzhinin, V.G. Long-Term Monitoring of Cytogenetic Aberrations in Adolescents of a Large Industrial Town. Russian Journal of Genetics 37, 1087–1090 (2001). https://doi.org/10.1023/A:1011925901507
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DOI: https://doi.org/10.1023/A:1011925901507