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Pet Ownership and Childhood Acute Leukemia (USA and Canada)


Objectives: For more than three decades there has been speculation regarding a possible role of zoonotic diseases in the development of human leukemia. This study investigated the potential relationship between exposure to pets and the development of childhood leukemia. Methods: Data from 2359 cases of acute leukemia from two large case–control studies were analyzed. Cases were individually matched to population controls on telephone exchange, age, and race. Conditional logistic regression was used to estimate odds ratios (OR) associated with pet ownership. Results: Overall, there was no association between pet ownership (either “any pet”, dog, or cat) and childhood acute leukemia (ORany pet:=1.01, 95% CI 0.89–1.2). Additionally, no relationship was found between exposure to an ill pet and childhood leukemia. Conclusion: The results of this analysis suggest that pet ownership (healthy or sick) is unrelated to an increased risk of childhood leukemia.

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  1. Bross IJD, Gibson R (1970) Cats and childhood leukemia. J Med 1: 180–187.

    Google Scholar 

  2. Buckley JD, Buckley CM, Ruccione K, et al. (1994) Epidemiological characteristics of childhood acute lymphocytic leukemia. Analysis by immunophenotype. Leukemia 8: 856–864.

    Google Scholar 

  3. Petridou E, Trichopoulos D, Kalapothaki V, et al. (1997) The risk profile of childhood leukemia in Greece: a nationwide case-control study. Br J Cancer 76: 1241–1247.

    Google Scholar 

  4. Donaldson LJ, Rankin J, Proctor S (1994) Is it possible to catch leukemia from a cat? Lancet 344: 971–972.

    Google Scholar 

  5. Ross JA, Severson RK, Pollock BH, Robison LL (1996) Childhood cancer in the United States. A geographical analysis of cases from the pediatric cooperative clinical trials groups, Cancer 77: 201–207.

    Google Scholar 

  6. Shu XO, Linet MS, Steinbuch M, et al. (1999) Breast-feeding and risk of childhood acute leukemia. J Natl Cancer Inst 91: 1765–1772.

    Google Scholar 

  7. Nishi M, Miyake H (1989) A case-control study of non-T cell acute lymphoblastic leukemia of children in Hokkaido, Japan. J Epidemiol Commun Health 43: 352–355.

    Google Scholar 

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Swensen, A.R., Ross, J.A., Shu, X.O. et al. Pet Ownership and Childhood Acute Leukemia (USA and Canada). Cancer Causes Control 12, 301–303 (2001).

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  • child
  • leukemia
  • pets