Skip to main content
Log in

Guidelines for Studies that Involve Placebo Controls: The Massachusetts Approach

  • Published:
Administration and Policy in Mental Health and Mental Health Services Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

REFERENCES

  • Appelbaum, P.S. (1996). Drug-free research in schizophrenia: An overview of the controversy. IRB: A Review of Human Subjects Research, 18, 1–5.

    Google Scholar 

  • Appelbaum, P.S. (1997). Rethinking the conduct of psychiatric research. Archives of General Psychiatry, 54, 117–120.

    PubMed  Google Scholar 

  • Appelbaum, P.S., Grisso, T., Frank, E., O'Donnell, S., & Kupfer, D.J. (1999). Competence of depressed patients for consent to research. American Journal of Psychiatry, 156, 1380–1384.

    PubMed  Google Scholar 

  • Bonnie, R.J. (1997). Research with cognitively impaired subjects: Unfinished business in the regulation of human research. Archives of General Psychiatry, 54, 105–111.

    PubMed  Google Scholar 

  • Capron, A.M. (1999). Ethical and human-rights issues in research on mental disorders that may affect decision-making capacity. New England Journal of Medicine, 340, 1430–1434.

    PubMed  Google Scholar 

  • Carpenter, W.T. (1999). The challenge to psychiatry as society's agent for mental illness treatment and research. American Journal Psychiatry, 156, 1307–1310.

    Google Scholar 

  • De Deyn, P.P., & D'Hooge, R. (1996). Placebos in clinical practice. Journal of Medical Ethics 22, 140–146.

    PubMed  Google Scholar 

  • Delano, S.J., & Zucker, J.L. (1994). Protecting mental health research subjects without prohibiting progress. Hospital and Community Psychiatry, 45, 601–603.

    PubMed  Google Scholar 

  • Elliott, C. (1997). Caring about risks: Are severely depressed patients competent to consent to research? Archives of General Psychiatry, 54, 113–116.

    PubMed  Google Scholar 

  • Grisso, T., & Appelbaum, P.A. (1995). Comparison of standards for assessing patients' capacities to make treatment decisions. American Journal of Psychiatry, 152, 1033–1037.

    PubMed  Google Scholar 

  • Hirschfeld, R.M.A., Winslade, W., & Krause T.L. (1997). Protecting subjects and fostering research. Archives of General Psychiatry, 54, 121–123.

    PubMed  Google Scholar 

  • Hrobjartsson, A. (1996). The uncontrollable placebo effect. European Journal of Clinical Pharmacology, 50, 345–348.

    PubMed  Google Scholar 

  • Leber, P. (1991). The future of controlled clinical trials. Psychopharmacology Bulletin, 27, 3–8.

    PubMed  Google Scholar 

  • Michaels, R. (1999). Are research ethics bad for our mental health? New England Journal of Medicine, 340, 1427–1430.

    PubMed  Google Scholar 

  • Schachter,D., Kleinman,I., Prendergast,P., Remington,G.,& Schertzer,S.(1994). The effect of psychopathology on the ability of schizophrenic patients to give informed consent. The Journal of Nervous and Mental Disease, 182, 360–362.

    PubMed  Google Scholar 

  • Wirshing,D.A., Wirshing,W.C., Marder,S.R., Liberman,R.P.,& Mintz,J.(1998). Informed consent:Assessment of comprehension. American Journal of Psychiatry, 155, 1508–1511.

    PubMed  Google Scholar 

  • Young,S.N.,& Annable,L.(1996). The use of placebos in psychiatry:A response to the draft document prepared by the Tri-Council Working Group. Journal of Psychiatry and Neuroscience, 21, 235–238.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Barreira, P., Albert, M., Altaffer, F. et al. Guidelines for Studies that Involve Placebo Controls: The Massachusetts Approach. Adm Policy Ment Health 28, 311–318 (2001). https://doi.org/10.1023/A:1011189614628

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1011189614628

Keywords

Navigation