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EEG Effects of Therapeutic Electric Stimulation of the Human Brain in the Posttraumatic Unconscious State

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Abstract

The effects of therapeutic SCS and transcranial electric stimulation on the functional activity of the brain in seven patients in the posttraumatic unconscious state were compared. The therapeutic transcranial stimulation was shown to exert a positive effect on the EEG and the characteristics of its spatial–temporal organization in most cases, which corresponds with positive shifts in the mental and motor sphere. The phasic character of changes in the bioelectric activity reflecting the sequence of involvement of the cerebral structures (primary activation of the deep frontal lobe divisions, activation of the subcortical-diencephalic structures, “activation” of the cortex) in the developing adaptive reactions, which helps understand their neurophysiological mechanisms, was described. It was established that the formation of the foci of persistent pathological activity with dominant characteristics in the brain is one of the possible complications of both SCS and transcranial electric stimulation. The mechanisms of their neurogenesis and the electrographic equivalents require further study. The data may serve as the basis for further clinical study of the influence of transcranial electric stimulation on the recovery of patients in postcomatose unconscious states.

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Authors and Affiliations

  1. Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, ul. Butlerova 5A, Moscow, 117865, Russia

    E. V. Sharova

  2. Burdenko Research Institute of Neurosurgery, Russian Academy of Medical Sciences, Moscow, Russia

    V. G. Amcheslavskii, A. A. Potapov, V. L. Anzimirov, O. S. Zaitsev, V. K. Emel'yanov & V. A. Shabalov

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  1. E. V. Sharova
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  2. V. G. Amcheslavskii
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  3. A. A. Potapov
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  4. V. L. Anzimirov
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  5. O. S. Zaitsev
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  6. V. K. Emel'yanov
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  7. V. A. Shabalov
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Sharova, E.V., Amcheslavskii, V.G., Potapov, A.A. et al. EEG Effects of Therapeutic Electric Stimulation of the Human Brain in the Posttraumatic Unconscious State. Human Physiology 27, 155–164 (2001). https://doi.org/10.1023/A:1011067014319

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