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Interhemispheric EEG Coherence during Rehabilitation of Patients after Severe Craniocerebral Injury

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Abstract

Dynamic clinical and EEG examinations (78 observations) were carried out in 17 patients suffering from severe craniocerebral injury during the course of their rehabilitation. Successful recovery of functions to the point of social and family readaptation was reached in 61% of patients (group I), and in 39% of patients the results were poor (group II). The complex of EEG coherence parameters (six rhythmic bands, mean coherence levels for 26 intrahemispheric and 8 interhemispheric derivation pairs, and the asymmetry coefficient of the EEG coherence) was analyzed in patients in comparison with normal values (20 right-handers). The rehabilitation was most efficient in cases when a certain dynamic sequence of patterns of interhemispheric relations of the EEG coherence was observed. First, a stable formation of right-hemispheric dominance was observed (most expressed in the centrofrontal areas in the θ range). This asymmetry pattern was phenomenologically associated with the recovery of the emotional sphere and positive dynamics in the motor and autonomic spheres. Later on, formation of the left-hemispheric dominance of the EEG coherence was observed (in the frontotemporal areas in the α–β ranges. This pattern was associated with complication of the cognitive functions. In the most severe forms of brain damage, the rehabilitation process was accompanied by changes in the interhemispheric EEG coherence with the elements of “stealing” from one of the hemispheres, which was correlated with clinical dynamics. Different types of the dynamics of reactive changes in the EEG coherence were revealed in patients of the two groups: successive formation of a generalized and then local modally specific reaction to afferent stimuli was observed in group I, while the generalized type of reactivity persisted in group II until the end of rehabilitation. It is suggested that the different sequence of formation of the interhemispheric EEG coherence reflects the involvement of different brain regulation systems in different orders into the integrative activity, i.e., some specific features of the rehabilitation process.

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Authors and Affiliations

  1. Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, ul. Butlerova 5a, Moscow, 117865, Russia

    L. A. Zhavoronkova

  2. Burdenko Institute of Neurosurgery, Russian Academy of Medical Sciences, ul. 4 Tverskaya-Yamskaya 16, Moscow, 125047, Russia

    O. A. Maksakova, N. Ya. Smirnova, O. A. Krotkova & V. L. Naidin

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  1. L. A. Zhavoronkova
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  2. O. A. Maksakova
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  4. O. A. Krotkova
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Zhavoronkova, L.A., Maksakova, O.A., Smirnova, N.Y. et al. Interhemispheric EEG Coherence during Rehabilitation of Patients after Severe Craniocerebral Injury. Human Physiology 27, 133–142 (2001). https://doi.org/10.1023/A:1011058513410

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