Abstract
This study examines the presence of hepatitis B as a possible precursor marker for HIV/AIDS in 10 districts of Zagreb, Croatia. There were a total of 931 cases of hepatitis B in Zagreb in the period 1979–1995, the annual rate ranging from 3.1 to 15.4 per 10,000. The highest relative risk for hepatitis B for the 1979–1995 period was in the Pescenica district (Relative risk (RR): 1.4). There were 108 cases of HIV/AIDS diagnosed in Croatia in the period 1986–1996, with 34% from Zagreb. The highest relative risk for HIV/AIDS was within the Pescenica district (RR: 2.3). Pescenica had also a significantly higher incidence of hepatitis B when compared to other districts (p = 0.005). The cumulative incidence of hepatitis B in Zagreb was directly related to levels of neighborhood discomfort as determined by an index including unemployment, inflation and housing conditions (p = 0.005). This research demonstrates that the poor areas of the city with higher incidence of hepatitis B hold the greatest threat for the spread of HIV/AIDS.
Similar content being viewed by others
References
Kura M, Hira S, Kohli M, et al. High occurrence of HVB among STD clinic attenders in Bombay, India. Int J STD AIDS 1998; 9: 231–233.
Panda S, Chatterjee A, Bhattacharjee S, et al. HIV, hepatitis B and sexual practices in the street-recruited injecting drug users of Calcutta: Risk perception verses observed risks. Int J STD AIDS 1998; 9: 214–218.
Singh J, Bhatia R, Gandhi J, et al. Outbreak of viral hepatitis B in a rural community in India linked to inadequately sterilized needles and syringes. Bull World Health Organ 1998; 76: 93–98.
Kapur S, Mittal A. Incidence of HIV and its precursors in blood supply in Delhi. Indian J Med Res 1998; 108: 45–50.
Rahlenbeck S. Infection with HIV, syphilis and hepatitis B in Ethiopia: A survey of blood donors. Int J STD AIDS 1997; 8: 261–264.
Chamberlin J, et al. Seroprevalence of hepatitis B virus among school-age children in the Stann Creek District of Belize, Central America. Am J Trop Med Hyg 1996; 55: 452–455.
Martin V, Cayla J, Moris M, et al. Predictive factors of HIV-infection in injecting drug users upon incarceration. Eur J Epidemiol 1998; 14: 327–331.
Santana Rodrigues O, Male Gil M, Hernandez Santana J, et al. Prevalence of serologic markers of HBV, HDV, HCV and HIV in non-injection drug users compared to injection drug users in Gran Caria, Spain. Eur J Epidemiol 1998; 14: 555–561.
Seage G, Mayer K, King W, et al. HIV and hepatitis B infection and risk behavior in young gay and bisexual men. Pub Health Reports 1997; 112: 158–167.
McQuillan G, Coleman P, Kruzen-Moran D, et al. Prevalence of hepatitis B virus infection in the United States: The national health and nutrition examination surveys, 1976–1998. AJPH 1999; 89: 14–18.
Massari V, Maison P, Desenclos J, et al. Six years of sentinel surveillance of hepatitis B in general practice in France. Eur J Epidemiol 1998; 14: 765–767.
Houweling H, Heisterkamp S, Wiessing L, et al. Methods for estimating HIV prevalence: A comparison of extrapolation from surveys on infection rate and risk behaviour with back-calculation for the Netherlands. Eur J Epidemiol 1998; 14: 645–652.
Garrett L. The Coming Plague. New York: Farrar, Straus and Giroux, 1994.
Pyle G, Parsons B, Gross W. A Geographic Information Systems (GIS) approach to community epidemiology in a North Carolina industrial county. Atlanta, GA: Centers for Disease Control and Prevention, National Center for Health Statistics. Compact Disk, 1997.
Statistical Yearbook. Republic of Croatia, Zagreb: Central Bureau of Statistics, 1991.
Kunst A, Mackenbach J. Measuring Socioeconomic Inequalities in Health. Geneva: World Health Organization, 1995.
Centers for Disease Control and Prevention. Annual Reports 1970–1995. Atlanta, GA: USPHS.
Palmovic D, Crnjakovic-Palmovic J. Vaccination against hepatitis B; results of the analysis of 2000 population members in Croatia. Eur J Epidemiol 1994; 10: 541–547.
Weinberg J, Simmonds S. Public health, epidemiology and war. Soc Sci Med 1995; 40: 1663–1669.
Burtenshaw D, Bateman M, Ashworth G. The European City: A western perspective. New York/Toronto: John Wiley and Sons, 1991.
Croatian National Institute of Public Health. Croatian Health Service Yearbook 1996, Zagreb, 1997.
Hubert M, Bajos N, Sandfort, eds. Sexual behaviour and HIV/AIDS in Europe. London: University College London, 1998.
Shannon G, Pyle G. The origin and diffusion of AIDS: A view from medical geography. Annals Assoc Amer Geog 1989; 79: 1–24.
Smallman-Raynor M, Cliff A, Haggett P. Atlas of AIDS. Cambridge: Blackwell, 1992.
Shannon G, Pyle G, Bashshur R. The geography of AIDS: Origin and course of an epidemic. New York/ London: Guilford Press, 1991.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Pyle, G.F., Oreskovic, S., Begovac, J. et al. Hepatitis B and HIV/AIDS in Zagreb: A district level analysis. Eur J Epidemiol 16, 927–936 (2000). https://doi.org/10.1023/A:1011010602831
Issue Date:
DOI: https://doi.org/10.1023/A:1011010602831