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Cholelithiasic Disease and Associated Factors in a Spanish Population

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Abstract

In order to analyze the factors associated with cholelithiasic disease, 1268 participants of a population sample were studied. On univariate analysis, 11 of the 23 variables included showed a statistically significant association (P < 0.05). Five of these variables, including obesity, triglyceride level, intake of hypolipidemic drugs, and a diet rich in cholesterol and saturated fats in women, and physical exercise in men, remained significantly associated after controlling for age. On multivariate analysis among women, a positive association was found with age (P < 0.001), obesity, and the use of hypolipidemic agents (P < 0.05) and a negative one with a diet rich in cholesterol and saturated fats (P < 0.05). Among men, the same analysis revealed there was a positive association with age (P < 0.001) and triglycerides (P < 0.05) and a negative one with physical exercise (P < 0.05). In conclusion, obesity and the use of hypolipidemic agents in women and triglycerides in men, were positively associated with cholelithiasic disease, independent of age, while negative associations included the intake of cholesterol and saturated fats in women and physical exercise in men.

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Authors and Affiliations

  1. Digestive Unit, Service of Internal Medicine, Hospital Francesc de Borja, Gandia, Valencia

    Francesc Devesa, Josefa Ferrando, Miguel Caldentey, Abdul Borghol & Maria José Moreno

  2. Department of Public Health, University of Alicante, Spain

    Andreu Nolasco & Joaquin Moncho

  3. Service of Digestive Disease, Hospital La Fe, Valencia, Spain

    Joaquin Berenguer

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  1. Francesc Devesa
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  2. Josefa Ferrando
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  3. Miguel Caldentey
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Devesa, F., Ferrando, J., Caldentey, M. et al. Cholelithiasic Disease and Associated Factors in a Spanish Population. Dig Dis Sci 46, 1424–1436 (2001). https://doi.org/10.1023/A:1010631619162

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