Skip to main content
SpringerLink
Log in

Anti-TNF Strategies

  • Published:
Sepsis

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Abraham E, Wunderink R, Silverman H, et al. Monoclonal antibody to human tumor necrosis factor alpha (TNFa MAb): Efficacy and safety in patients with the sepsis syndrome. JAMA 1995;273:934–941.

    Google Scholar 

  2. Cohen J, Carlet J, for the INTERSEPT Study Group. INTERSEPT: An international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-a in patients with sepsis. Crit Care Med 1996;24: 1431–1440.

    Google Scholar 

  3. Reinhart K, Wiegand-Lohnert C, Grimminger F, et al. Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment,MAK195F, in patients with sepsis and septic shock: A multicenter, randomized, placebo-controlled, dose-ranging study. Crit Care Med 1996;24:733–742.

    Google Scholar 

  4. Fisher CJ, Agosti JM, Opal SM, et al. Treatment of patients with septic shock with tumor necrosis factor receptor Fc fusion protein. N Engl J Med 1996;334:1697–1702.

    Google Scholar 

  5. Abraham E, Glauser MP, Butler T, et al. p55 tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock: A placebo controlled, randomized, double-blind, multi-center clinical trial. JAMA 1997;277:1531–1538.

    Google Scholar 

  6. Evans TJ, Moyes D, Carpenter A, et al. Protective effect of 55-but not 75-kD soluble tumor necrosis factor receptor-immunoglobulin G fusion proteins in an animal model of gram-negative sepsis. J Exp Med 1999;180:2173–2179.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Pulmonary and Critical Care Medicine, University of Colorado Health Sciences Center, Denver, CO

    Edward Abraham

Authors
  1. Edward Abraham
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Abraham, E. Anti-TNF Strategies. Sepsis 1, 19–20 (1997). https://doi.org/10.1023/A:1009703132434

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1009703132434

Keywords

Search

Navigation