Georges AJ, Leroy EM, Renaut AA, et al. Ebola hemorrhagic fever outbreaks in Gabon, 1994–1997: epidemiologic and health control issues. J Inf Dis 1999; 179(Suppl 1): 65–75.
Baize S, Leroy EM, Georges-Courbot M-C, et al. Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients. Nature Med 1999; 5: 423–426.
Miller T, Beausang LA, Meneghini M, Lidgard G. Deathinduced changes to the nuclear matrix: The use of anti-nuclear matrix antibodies to study agents of apoptosis. BioTechniques 1993; 15: 1042–1047.
World Health Organization. Ebola haemorrhagic fever in Sudan, 1976. Report of a world health organization study team. Bull WHO 1978; 56: 247–270.
Baskerville A, Fisher-Hoch SP, Neild GH, Dowsett AB. Ultrastructural pathology of experimental Ebola haemorrhagic fever virus infection. J Pathol 1985; 147: 199–209.
Fisher-Hoch SP, Platt GS, Neild GH, et al. Pathophysiology of shock and hemorrhage in a fulminating viral infection (Ebola). J Inf Dis 1985; 152: 887–894.
Ryabchikova EI, Kolesnikova LV, Luchko SV. An analysis of features of pathogenesis in two animal models of Ebola virus infection. J Inf Dis 1999; 179(Suppl I): S199–202.
Connolly BM, Steele KE, Davis KJ, et al. Pathogenesis of experimental Ebola virus infection in guinea pigs. J Inf Dis 1999; 179(Suppl I): S203–217.
Wool-Lewis RJ, Bates P. Characterization of Ebola virus entry by using pseudotyped viruses: identification of receptordeficient cell lines. J Virol 1998; 72: 3155–3160.
Sanchez A, Yang Z-Y, Xu L, Nabel GJ, Crews T, Peters CJ. Biochemical analysis of the secreted and virion glycoproteins of Ebola virus. J Virol 1998; 72: 6442–6447.
Yang Z-Y, Delgado R, Xu L, et al. Distinct cellular interactions of secreted and transmembrane Ebola virus glycoproteins. Science 1998; 279: 1034–1037.
Volchkov VE, Volchkova VA, Slenczka W, Klenk H-D, Feldmann H. Release of viral glycoproteins during Ebola virus infection. Virol 1998; 245: 110–119.
Boudet F, Lecoeur H, Gougeon M-L. Apoptosis associated with ex vivo down-regulation of Bcl-2 and up-regulation of Fas in potential cytotoxic CD8+ T lymphocytes during HIV infection. J Immunol 1996; 156: 2282–2293.
Alexander-Miller MA, Derby MA, Sarin A, Henkart PA, Berzofsky JA. Supraoptimal peptide-major histocompatibility complex causes a decrease in Bcl-2 levels and allows tumor necrosis factor ® receptor II-mediated apoptosis of cytotoxic T lymphocytes. J Exp Med 1998; 188: 1391–1399.
Gallimore A, Glithero A, Godkin A, et al. Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes vizualized using soluble tetrameric major histocompatibility complex class-I-peptide complexes. J Exp Med 1998; 187: 1383–1393.
Moskophidis D, Lechner F, Pircher H, Zinkernagel RM. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 1993; 362: 758–761.
Dhein J, Walczak H, B¨aumler C, Debatin KM, Krammer PH. Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 1995; 373: 438–441.
Zheng L, Fisher G, Miller RE, Peschon J, Lynch DH, Lenardo MJ. Induction of apoptosis in mature T cells by tumor necrosis factor. Nature 1995; 377: 348–351.
Liu Y, Janeway CA. Interferon ° plays a critical role in induced cell death of effector cell: a possible third mechanism of selftolerance. J Exp Med 1990; 172: 1735–1739.
Suda T, Hashimoto H, Tanaka M, Ochi T, Nagata S. Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing. J Exp Med 1997; 186: 2045–2050.
Villinger F, Rollin PE, Brar SS, et al. Markedly elevated levels of interferon (IFN)-°, IFN-®, interleukin (IL)-2, IL-10, and tumor necrosis factor-® associated with fatal Ebola virus infection. J Inf Dis 1999; 179(Suppl 1): S188–191.
Yoshida H, Sumichika H, Hamano S, et al. Induction of apoptosis of T cells by infecting mice with murine cytomegalovirus. J Virol 1995; 69: 4769–4775.
Gummuluru S, Novembre FJ, Lewis M, Gelbard HA, Dewhurst S. Apoptosis correlates with immune activation in intestinal lymphoid tissue from macaques acutely infected by a highly enteropathic simian immunodeficiency virus, SIVsmmPBj14. Virol 1996; 225: 21–32.
Summerfield A, Kn¨otig SM, McCullough KC. Lymphocyte apoptosis during classical swine fever: implication of activation-induced cell death. J Virol 1998; 72: 1853–1861.
Feldmann H, Bugany H, Mahner F, Klenk HD, Drenckhahn D, Schnittler HJ. Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages. J Virol 1996; 70: 2208–2214.
Schnittler HJ, Feldmann H. Molecular pathogenesis of filovirus infections: role of macrophages and endothelial cells. In: Klenk HD, ed. Marburg and Ebola Viruses. Berlin: Springer-Verlag 1999: 175–204.