Skip to main content
Log in

9[1-(2-Hydroxy ethoxy)-3-hydroxy propyl] guanine: a nucleoside analog

  • Note
  • Published:
Journal of Chemical Crystallography Aims and scope Submit manuscript

Abstract

The compound 9[1-(2-hydroxy ethoxy)-3-hydroxy propyl] guanine crystalizes in the tetragonal system, space group P41212 with a = 11.106 (1), c = 20.558 (2) Å, and Z = 8. The acyclic chain C1′¯O1′¯C4′¯C5′¯O5′ is in the extended configuration and the glycosidic torsion angle (C4¯N9¯C1′¯O1′) is 125.1 (8)°. The molecules are held together by Van der Waal's forces.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Elion, G.B.; Furman, P.A.; Fyfe, J.A.; de Miranda, P.; Beauchamp, L.; Schaeffer, H. J. Proc. Natl. Acad. Sc. USA, 1977, 74, 5717.

    Google Scholar 

  2. Schaeffer, H.J.; Beauchamp, L.; de Miranda, P.; Elion, G.B.; Bauer, D.J.; Collins, P. Nature (London) 1978, 272, 583.

    Google Scholar 

  3. Scheiner, P.; Geer, A.; Bucknor, A.M.; Imbach, J.L.; Schinazi, R.F. J. Med. Chem. 1989, 32, 73.

    Google Scholar 

  4. Enraf-Nonius, CAD-4 Software; Enraf-Nonius: Delft, Holland, 1988.

  5. Taylor, R; Kennard, O. J. Chem. Soc. 1982, 104, 3209.

    Google Scholar 

  6. Allen, F.H.; Kennard, O.; Watson, D.G.; Brammer, L.; Orpen, A.G.; Taylor, R. J. Chem. Soc. Perkin Trans. 2, 1987, S1.

    Google Scholar 

  7. Main, P.; Fisco, S.J.; Hull, S.E.; Lessinger, L.; Germain, G.; Declercq, J.P.; Woolfson, N.M. MULTAN 80: A System of Computer Programs for the Automatic Solution of Crystal Structure from X-ray Diffraction Data; University of York, England & Louvain: Belgium.

  8. Sheldrick, G.M. SHELXL93: Program for Refinement of Crystal Structures; University of Gottingen: Germany, 1993.

    Google Scholar 

  9. Johnson, C.K. ORTEP-II Report ORNL-5138; Oak Ridge National Laboratory: TN, 1976.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mazumder, G., De, M., Mukhopadhyay, A. et al. 9[1-(2-Hydroxy ethoxy)-3-hydroxy propyl] guanine: a nucleoside analog. Journal of Chemical Crystallography 29, 1137–1139 (1999). https://doi.org/10.1023/A:1009570111108

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1009570111108

Navigation