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Comparative Study of DNA-Specific Dyes of the Indole and Benzimidazole Series

Abstract

Various models of complex formation of low-molecular ligands with DNA are considered. Using the Scatchard model, parameters of binding of fluorescent monophenylindole, monophenylbenzimidazole, and bisbenzimidazole dyes with calf thymus DNA were evaluated. By means of graphic (nonparametric) and correlation analysis, various spectral and complexation properties of these dyes in the presence of DNA are compared.

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Sibirtsev, V.S., Garabadzhiu, A.V. & Ivanov, S.D. Comparative Study of DNA-Specific Dyes of the Indole and Benzimidazole Series. Russian Journal of Bioorganic Chemistry 27, 57–65 (2001). https://doi.org/10.1023/A:1009535320077

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  • DOI: https://doi.org/10.1023/A:1009535320077

  • DNA
  • complex formation
  • benzimidazoles
  • phenylindoles