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Vanadium toxicology – an assessment of general health, haematological aspects and energy response in an Indian catfish Clarias batrachus (Linn)

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Abstract

The pervasive occurrence of vanadium in nature and its use in various industrial processes has increased its inputs in the environment. This has prompted us to elucidate the impact of vanadium on aquatic environ-ment, the primary body for industrial effluent discharge. The energy response of the fish, Clarias batra-chus, its haematological status including haemoglobin (Hb), haematocrit (Ht), leutocrit (Lt), mean corpuscular haemoglobin (MCH), mean corpuscular volume (MCV), mean corpuscular haemoglobin concen-tration (MCHC) etc. And overall general health conditions have been observed to be significantly hampered leading to deleterious alterations in the general metabolism of the fish following long term exposure to vana-date. The increase in muscle and tissue lactic acid (2–12 fold) in association with decrease in pyruvic acid (72% in mucle; 26% in liver) reflect a shift towards an anaerobic metabolism of the fish. We conclude that vanadium could be toxic for the fish in question under long term exposure at the doses under observation (2–10 mg L).© Rapid Science 1998

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References

  • Burton DT, Spehar AM. 1971 A re-evaluation of the anaerobic end products of fresh water fish exposed to environmental hypoxia. Comp Biochem Physiol 40A, 945–949.

    Google Scholar 

  • Chakraborty A, Bhattacharjee S, Chatterjee M. 1995 Alterations in enzymes in an Indian cat fish Clarias batrachus (L) exposed to vanadium. Bull Environ Contam Toxicol 54 281–288.

    Google Scholar 

  • Dacie J, Lewis K. 1968 Practical Haematology. London: Churchill.

    Google Scholar 

  • Duthie GG, Tort L. 1985 Effects of dorsal aortic cannulation on the respiration and haematology of mediterranian living Scyliorhinus canicula. Comp Biochem Physiol 81A, 879–883.

    Google Scholar 

  • Eyal A, Moran ET. 1984 Egg changes associated with reduced interior quality because of dietary vanadium toxicity in the hen. Poult Sci 63, 1378–1385.

    Google Scholar 

  • Heath AG. 1984 Changes in tissue adenylates and water content of blue gill, Lepomis macrochirus exposed to copper. J Fish Biol 24, 299–310.

    Google Scholar 

  • Hilmy AM, Domiaty NAEL, Daabiees AY, Abdellatife HA. 1987 Some physiological and biochemical indices of zinc toxicity in two fresh water fishes, Clarias lazera and Tilapia zilli. Comp Biochem Physiol 87C, 297–301.

    Google Scholar 

  • Jagadeesh KB, Shaffi SA, Jeelani S. 1989 Vanadium induced changes in glycogen content of Clarias batrachus (Linn.) and Channa punctatus (Bloch). Acta Physiol Hung 74, 43–48.

    Google Scholar 

  • Johnson I. 1988 The effects of combinations of heavy metals, hyoxia and salinity on ion regulation in Crangon crangon (L) and Carcinus maenas (L). Comp Biochem Physiol 91C, 459–463.

    Google Scholar 

  • Lal H, Misra V, Viswanathan PN, Krishna Murti CR. 1984 Effect of synthetic detergents on some of the behavioural patterns of fish fingerlings (Cirrhina mrigala) and its relation to ecotoxicology. Bull Environ Contam Toxicol 32, 109–115.

    Google Scholar 

  • Lowry OH, Rosenbrough NJ, Farr, AL, Randall, RL. 1951 Protein measurement with Folin phenol reagent. J Biol Chem 193, 265–275.

    Google Scholar 

  • Mosior M, Krawczak ST, Wrobel A, Bialas WA, Gomulkiewicz Z. 1992 The effect of arsenate and vanadate ions on the critical cell volume of bovine erythrocytes. Gen Physiol Biophys 11, 337–343.

    Google Scholar 

  • Nriagu JO, Pacyna JM. 1988 Quantitative assessment of worldwide contamination of air, water and soils by trace metals. Nature 333, 134–139.

    Google Scholar 

  • Oser BL. 1979 Hawk's Physiological Chemistry, New York: McGraw Hill.

    Google Scholar 

  • Paschoa et al. 1987 Localization of vanadium containing particles in the lungs of uranium-vanadium miners. Biol Trace Elem Res 13, 275–282.

    Google Scholar 

  • Ray D, Banerjee SK, Chatterjee M. 1990 Bioaccumulation of nickel and vanadium in the cat fish, Clarias batrachus. J Inorg Biochem 38, 169–172.

    Google Scholar 

  • Rowe DW, Sprague JB, Heming TA. 1983 Sublethal effects of treated liquid effluent from a petroleum refinery: 1. Chronic toxicity to flagfish. Aqua Toxicol 3, 149–160.

    Google Scholar 

  • Sharma RP, Coulombe RA, Srisuchart B. 1986 Effects of dietary vanadium exposure on levels of regional brain neurotransmitters and their metabolites. Biochem Pharmacol 35, 461–465.

    Google Scholar 

  • Sigal N, Cattaneo J, Segal IH. 1965 Glycogen accumulation by wild type and uridine disphosphate glucose pyrophosphorylase-negative strains of Escherichia coli. Arch Biochem Biophys 108, 440–451.

    Google Scholar 

  • Simons DJB. 1979 Vanadate: A new tool for biologist. Nature 281, 337–338.

    Google Scholar 

  • Torres P, Tort L, Planas J, Flos R. 1986 Effects of confinement stress and additional zinc treatment on some blood parameters in the dog fish, Scyliorhinus canicula. Comp Biochem Physiol 83C, 89–92.

    Google Scholar 

  • Tort L, Crespo S, Balasch J. 1982 Oxygen consumption of the dog fish gill tissue following zinc treatment. Comp Biochem Physiol 72C, 145–148.

    Google Scholar 

  • WHO. 1988 In: Vanadium: Environmental Health Criteria, Geneva: WHO.

    Google Scholar 

  • Zaporowska H, Wasilewski W. 1992 Haematological effects of vanadium on living organisms. Comp Biochem Physiol 102C, 223–231.

    Google Scholar 

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Chakraborty, A., Oinam, S., Karmakar, R. et al. Vanadium toxicology – an assessment of general health, haematological aspects and energy response in an Indian catfish Clarias batrachus (Linn). Biometals 11, 95–100 (1998). https://doi.org/10.1023/A:1009269726689

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