Abstract
Sulphur-free lignin biopolymer and its oxidized and reduced derivatives have been prepared and their inhibitory activity against u.v.-induced mutagenesis in Euglena gracilis was evaluated. The structure- and dose-dependent anti-u.v. activity of lignins was observed at concentrations higher than 250 μg ml−1. The oxidized lignin showed the most antimutagenic activity, followed by the reduced lignin and the unmodified lignin had the least antimutagenic activity.
References
Ebringer, L. 1990 Interaction of drugs with extracellular genetic elements and its consequences. Teratogenesis, Carcinogenesis, Mutagenesis 10, 477-501.
Ebringer, L., Dobias, J., Krajčovič, J., Polónyi, J., Križková, L. & Lahitová, N. 1996 Antimutagens reduce ofloxacin-induced bleaching in Euglena gracilis. Mutation Research 359, 85-93.
Ebringer, L., Križková, L., Polónyi, J., Dobias, J. & Lahitová, N. 1999 Antimutagenicity of lignin in vitro. Anticancer Research 19, 569-572.
Greenblatt, C.L. & Schi., J. A. 1959 A pheophytin-like pigment in dark-adapted Euglena gracilis. Journal of Protozoology 6, 23-28.
Lu, F.J., Chu, L.H. & Gau, R.J. 1998 Free radical-scavenging properties of lignin. Nutrition and Cancer 30, 31-38.
Rozema, J., Van de Staaij, J., Björn, L.O. & Caldwell, M. 1997 UV-B as an environmental factor in plant life: stress and regulation. Trends in Ecology and Evolution 12, 22-28.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Belicová, A., Krajčovič, J., Križková, L. et al. Anti-u.v. activity of lignin biopolymers on Euglena gracilis. World Journal of Microbiology and Biotechnology 16, 91–93 (2000). https://doi.org/10.1023/A:1008978231230
Issue Date:
DOI: https://doi.org/10.1023/A:1008978231230