In vitro evaluation of the antifungal activity of Allium sativum bulb extract against Trichophyton rubrum, a human skin pathogen

  • J. Karunyal Samuel
  • B. Andrews
  • H. Shyla Jebashree


The aqueous extract of Allium sativum bulbs showed an antifungal effect against the fungal skin pathogen, Trichophyton rubrum, isolated from infected patients. For a given concentration (200 mg of bulbs/1 ml), the volume of the aqueous garlic extract loaded on to the discs, and the diameter of the inhibitory zone formed around the disc on the fungal lawn showed positive correlation. Extract-included microbial assay confirmed the antifungal effect of Allium sativum. The extract was not heat stable, it lost its antifungal property above 60 °C.

Allium sativum antifungal effect Trichophyton rubrum 


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Copyright information

© Kluwer Academic Publishers 2000

Authors and Affiliations

  • J. Karunyal Samuel
    • 1
  • B. Andrews
    • 1
  • H. Shyla Jebashree
    • 1
  1. 1.India

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