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Structure of dextran–magnetite complex: relation between conformation of dextran chains covering core and its molecular weight

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Abstract

A homologous series of dextran–magnetite complex (DM) was synthesized using alkali-treated dextrans with various molecular weights from 1800 to 27 000. The structure of DM particles in water, particularly effect on molecular weight of dextran, was studied. The number of dextran chains binding to a core is possibly determined by the steric hindrance between dextran chains covering core. The conformation of dextran chains may change from a fully extended state to a random-coiled state with an increase in molecular weight.

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References

  1. M. HASEGAWA and S. HOKKOKU, US Patent No. 4,101,435 (1978).

  2. M. HASEGAWA, S. MARUNO, T. KAWAGUCHI and T. MORIYA, in Proceedings of the 6th International Conference on Ferrites, Kyoto,1992, p. 1007.

  3. M. OHGUSHI, K. NAGAYAMA and A. WADA, J. Magn. Reson. 29 (1978) 599.

    Google Scholar 

  4. K. YAGI, T. HANAICHI, M. HASEGAWA, T. KAWAGUCHI, S. MARUNO and N. FUJITSUKA, in Proceedings of the 4th International Conference on Biointeractions, Leiden, 1993, p. 53.

  5. T. MORIYA, M. HASEGAWA, H. KATSUSE, S. MARUNO, T. KAWAGUCHI and H. KAWAGUCHI, in Proceedings of the 6th International Conference on Ferrites, Kyoto, 1992, p. 1023.

  6. S. SAINI, D. D. STARK, P. F. HAHN, J. WITTENBERG, T. J. BRADY and J. T. FERRUCCI, Radiology 162 (1987) 211.

    PubMed  Google Scholar 

  7. D. D. STARK, R. WEISSLEDER, G. ELIZONDO, P. F. HAHN, S. SAINI, L. E. TODD, J. WITTENBERG and J. T. FERRUCCI, ibid. 168 (1988) 297.

    PubMed  Google Scholar 

  8. R. WEISSLEDER, D. D. STARK, B. L. ENGELSTAD, B. R. BACON, C. C. COMPTON, D. L. WHITE, P. JACOBS and J. LEWIS, Amer. J. Roentgenol. 152 (1989) 167.

    Google Scholar 

  9. M. HASEGAWA, S. MARUNO, M. TOBITA and N. FUJITSUKA, in Proceedings of the 8th European Conference on Biomaterials, Heidelberg, 1989, p. 517.

  10. Y. KAWAMURA, K. ENDO, Y. WATANABE, T. SAGA, T. NAKAI, H. HIKITA, K. KAGAWA and J. KONISHI, Radiology 174 (1990) 357.

    PubMed  Google Scholar 

  11. R. L. MAGIN, G. BACIC, M. R. NIESMAN, J. C. ALAMEDA. JR, S. M. WRIGHT and H. M. SWARTZ, Magn. Reson. Med. 20 (1991) 1.

    PubMed  Google Scholar 

  12. T. HANAICHI, S. MARUNO, M. HASEGAWA and T. KAWAGUCHI, in Proceedings of the 13th International Congress on Electron Microscopy, Paris, 1994, Vol. 3B, p. 913.

    Google Scholar 

  13. M. HASEGAWA, T. HANAICHI, H. SHOJI, T. KAWAGUCHI and S. MARUNO, Jpn. J. Appl. Phys. 37 (1998) 1029.

    Google Scholar 

  14. J. S. G. COX, G. R. KENNEDY, J. KING, P. R. MARSHALL and D. RUTHERFORD, J. Pharm. Pharmacol. 24 (1972) 513.

    PubMed  Google Scholar 

  15. H. P. KLUG and I. E. ALEXANDER, "X-ray diffraction procedures", (Wiley, New York, 1954) Chap. 9.

    Google Scholar 

  16. H. R. SHELL, Anal. Chem. 22 (1950) 326.

    Google Scholar 

  17. R. C. WEAST and M. J. ASTLE (eds), "CRC handbook of chemistry and physics" 62nd edn (CRC Press, Boca Raton, Florida, 1981) p. B-109.

    Google Scholar 

  18. T. KATO, K. NAKAMURA, M. KAWAGUCHI and A. TAKAHASHI, Polymer J. 13 (1981) 1037.

    Google Scholar 

  19. R. C. WEAST and M. J. ASTLE (eds), “CRC handbook of chemistry and physics” 62nd edn (CRC Press, Boca Raton, Florida, 1981) p. C-263.

    Google Scholar 

  20. F. R. SENTI, N. N. HELLMAN, N. H. LUDWIG, G. E. BABCOCK, R. TOBIN, C. A. GLASS and B. L. LAMBERTS, J. Polym. Sci. 17 (1955) 527.

    Google Scholar 

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Kawaguchi, T., Hasegawa, M. Structure of dextran–magnetite complex: relation between conformation of dextran chains covering core and its molecular weight. Journal of Materials Science: Materials in Medicine 11, 31–35 (2000). https://doi.org/10.1023/A:1008933601813

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