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Stability of enzymes in water/organic co-solvent mixtures

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Biotechnology Techniques

Abstract

The half lives of polyphenol oxidase and trypsin at 50% (v/v) co-solvent (water miscible) were from 23 to 176 h when polarity index of the co-solvent was >5.8 or if the co-solvent was an alcohol. Polyphenol oxidase, trypsin, chymotrypsin and β-glucosidase lost only 10% activity in such water/organic co-solvent mixtures when the organic co-solvents were present in the concentration ranges of 55–90%, 60–78%, 15–70% and 7–25% respectively. © Rapid Science Ltd. 1998

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Tyagi, R., Gupta, M.N. Stability of enzymes in water/organic co-solvent mixtures. Biotechnology Techniques 12, 569–570 (1998). https://doi.org/10.1023/A:1008820018265

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  • DOI: https://doi.org/10.1023/A:1008820018265

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