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Signal Transduction in Resistance to Plant Viruses

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Abstract

Salicylic acid is part of a signal transduction pathway that induces resistance to viruses, bacteria and fungi. In tobacco and Arabidopsis the defensive signal transduction pathway branches downstream of salicylic acid. One branch induces PR-1 proteins and resistance to bacteria and fungi, while the other triggers induction of resistance to RNA and DNA viruses. This virus-specific branch can be activated using antimycin A and cyanide, or inhibited with salicylhydroxamic acid, suggesting a role for alternative oxidase in resistance to viruses. The virus-specific defensive pathway activates multiple resistance mechanisms. In tobacco, salicylic acid induces resistance to systemic movement of cucumber mosaic virus but has no effect on its replication or cell-to-cell movement. However, in the case of tobacco mosaic virus in tobacco, salicylic acid appears to induce interference with the synthesis of viral RNA.

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Author notes

  1. John P. Carr

    Present address: Horticulture Unit, CSIRO Plant Industry, Merbein, Victoria, 3505, Australia

Authors and Affiliations

  1. Department of Plant Sciences, University of Cambridge, Downing Street, Cambridge, CB2 3EA, UK

    Alex M. Murphy, Androulla Gilliland, Chui Eng Wong, Joanne West & John P. Carr

  2. Department of Plant Sciences, University of Cambridge, Downing Street, Cambridge, CB2 3EA, UK

    Davinder P. Singh

Authors
  1. Alex M. Murphy
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  2. Androulla Gilliland
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  3. Chui Eng Wong
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  4. Joanne West
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  5. Davinder P. Singh
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  6. John P. Carr
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Correspondence to Davinder P. Singh.

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Murphy, A.M., Gilliland, A., Eng Wong, C. et al. Signal Transduction in Resistance to Plant Viruses. European Journal of Plant Pathology 107, 121–128 (2001). https://doi.org/10.1023/A:1008732123834

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