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Complete Nucleotide Sequence Analysis of a Western Pacific Dengue-1 Virus Strain

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Abstract

We have determined the complete nucleotide sequence and the deduced amino acid polypeptide sequence of the genome of a dengue-1 (DEN-1) virus strain isolated from a patient on Nauru in the Western Pacific in 1974 (West Pac 74). The complete genome is 10,735 nucleotides in length and contains a single long open reading frame of 10,176 nucleotides encoding a polyprotein of 3392 amino acids. When compared to DEN-1 Singapore S275/90, the nucleotide and amino acid sequence homology are 94% and 97.8%, respectively.

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Authors and Affiliations

  1. Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland, 20889-5607

    Beena Puri, William Nelson, Kevin R. Porter & Curtis G. Hayes

  2. Virology Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Fredrick, Maryland, 21702-5011

    Erik A. Henchal

Authors
  1. Beena Puri
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  2. William Nelson
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  3. Kevin R. Porter
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  4. Erik A. Henchal
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  5. Curtis G. Hayes
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Puri, B., Nelson, W., Porter, K.R. et al. Complete Nucleotide Sequence Analysis of a Western Pacific Dengue-1 Virus Strain. Virus Genes 17, 85–88 (1998). https://doi.org/10.1023/A:1008009202695

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  • DOI: https://doi.org/10.1023/A:1008009202695

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