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Hypolipidemic effect of flavonoids from Solanum melongena

Plant Foods for Human Nutrition volume 51, pages 321–330 (1997)Cite this article

Abstract

Flavonoids extracted from the fruits of Solanum melongena (Brinjal) orally administered at a dose of 1 mg/100 g BW/day showed significant hypolipidemic action in normal and cholesterol fed rats. HMG CoA reductase activity was found to be enhanced, while activities of glucose-6-phosphate dehydrogenase and malate dehydrogenase were significantly reduced. Activities of lipoprotein lipase and plasma LCAT showed significant enhancement. A significant increase in the concentrations of hepatic and fecal bile acids and fecal neutral sterols was also observed indicating a higher rate of degradation of cholesterol.

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Authors and Affiliations

  1. Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram-, 695 581, India

    S. Sudheesh, G. Presannakumar, S. Vijayakumar & N. R. Vijayalakshmi

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  1. S. Sudheesh
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  2. G. Presannakumar
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  3. S. Vijayakumar
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  4. N. R. Vijayalakshmi
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Sudheesh, S., Presannakumar, G., Vijayakumar, S. et al. Hypolipidemic effect of flavonoids from Solanum melongena. Plant Foods Hum Nutr 51, 321–330 (1997). https://doi.org/10.1023/A:1007965927434

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  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1007965927434

  • Solanum melongena
  • Flavonoid
  • HMG CoA
  • Glucose-6-phosphate dehydrogenase
  • Malate dehydrogenase
  • Lipoproteinlipase
  • LCAT