Skip to main content
SpringerLink
Log in

Personal Viewpoint: New Developments in the Therapy of Diabetic Hypertensive Disease. The ABCD Study Adds to Strong Evidence Favoring the Prime Use of ACE Inhibitors

  • Published:
Cardiovascular Drugs and Therapy Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Mehler PS, Jeffers BW, Estacio R, Schrier RW. Associations of hypertension and complications in non-insulin-dependent diabetes mellitus. Am J Hypertens 1997;10:152-161.

    Google Scholar 

  2. JNC VI. Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Arch Intern Med 1997;157:2413-2446.

    Google Scholar 

  3. Klag MJ, Whelton PK, Randall BL, et al. Blood pressure and end-stage renal disease in men. N Engl J Med 1996;334: 13-18.

    Google Scholar 

  4. Perry HM, Miller P, Fornoff JR, et al. Early predictors of 15-year end-stage renal disease in hypertensive patients. Hypertension 1995;25:587-594.

    Google Scholar 

  5. Weidmann P, Boehlen LM, de Courten M. Pathogenesis and treatment of hypertension associated with diabetes mellitus. Am Heart J 1993;125:1498-1513.

    Google Scholar 

  6. Ritz E, Keller C, Bergis K, Strojek K. Pathogenesis and course of renal disease in IDDM/NIDDM. Differences and similarities. Am J Hypertens 1997;10:202S-207S.

    Google Scholar 

  7. Mogensen CE. Angiotensin converting enzyme inhibitors and diabetic nephropathy. Br Med J 1992;3-4:327-328.

    Google Scholar 

  8. Mogensen CE, Keane WF, Bennett PH, et al. Prevention of diabetic renal disease with special reference to microalbuminuria. Lancet 1995;346:1080-1084.

    Google Scholar 

  9. Diabetics Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulindependent diabetes mellitus. Engl J Med 1993;329:977-986.

    Google Scholar 

  10. Schmitz A. Microalbuminuria, blood pressure, metabolic control and renal involvement. Am J Hypertens 1997;10: 189S-197S.

  11. Laffel LM, McGill JB, Gans DJ. The beneficial effect of angiotensin-converting enzyme inhibition with captopril on diabetic nephropathy in normotensive IDDM patients with microalbuminuria. Am J Med 1995;99:497-504.

    Google Scholar 

  12. ABCD Study (Appropriate Blood Pressure Control in Diabetes). The effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with non-insulin-dependent diabetes and hypertension. N Engl J Med 1998; 338:645-652.

    Google Scholar 

  13. FACET Trial, Tatti P, Pahor M, et al. Results of the Fosinopril Amlodipine Cardiovascular Events Trial (FACET) in hypertensive patients with non-insulin dependent diabetes mellitus (NIDDM). Circulation 1997;96(Suppl. 1):1-764.

    Google Scholar 

  14. Estacio RO, Jeffers BW, Hiatt WH, et al. The effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with non-insulin-dependent diabetes and hypertension. N Engl J Med 1998; 338:645-652.

    Google Scholar 

  15. Nesto RW, Zarich S. Acute myocardial infarction in diabetes mellitus. Lessons learned from ACE inhibition. Circulation 1998;97:12-15.

    Google Scholar 

  16. Grossman E, Messerli FH, Grodzicki T, Kowey P. Should a moratorium be placed on sublingual nifedipine capsules given for hypertensive emergencies and pseudoemergencies? JAMA 1996;276:1328-1331.

    Google Scholar 

  17. Grassi G, Cattaneo BM, Seravalle G, et al. Effects of chronic ACE inhibition on sympathetic nerve traffic and baroreflex control of circulation in heart failure. Circulation 1997;96: 1173-1179.

    Google Scholar 

  18. Tatti P, Pahor M, Byington R, et al. Results of the Fosinopril Amlodipine Cardiovascular Events Trial (FACET) in hypertensive patients with non-insulin dependent diabetes mellitus (NIDDM) (abstr). Circulation 1997;96(Suppl. D):1-764.

    Google Scholar 

  19. Isshiki T, Amodeo C, Messerli FH, et al. Diltiazem maintains renal vosodilation without hyperfiltration in hypertension: Studies in essential hypertensive man and the spontaneously hypertensive rat. Cardiovasc Drugs Therp 1987;1: 359-366.

    Google Scholar 

  20. Anderson S. Renal hemodynamic effects of calcium antagonists in rats with reduced renal mass. Hypertension 1991;17:288-295.

    Google Scholar 

  21. Maki DD, Ma JZ, Louis TA, Kasiske BL. Long-term effects of antihypertensive agents on proteinuria and renal function. Arch Intern Med 1995;155:1073-1080.

    Google Scholar 

  22. Bakris GL, Copley JB, Vicknair N, et al. Calcium channel blockers versus other antihypertensive therapies on progression of NIDDM associated nephropathy. Kidney Int 1996;50:1641-1650.

    Google Scholar 

  23. Wang PH. When should ACE inhibitors be given to normotensive patients with IDDM? Lancet 1997;349:1782-1783.

    Google Scholar 

  24. Orth SR, Ritz E, Schrier RW. Perspectives in clinical nephrology: The renal risks of smoking. Kidney Int 1997;51: 1669-1677.

    Google Scholar 

  25. Bretzel RG. Effects of antihypertensive drugs on renal function in patients with diabetic nephropathy. Am J Hypertens 1997;10:208S-217S.

    Google Scholar 

  26. Parving H-H, Andersen AR, Smidt UM, et al. Effect of antihypertensive treatment on kidney function in diabetic nephropathy. Br Med J 1987;294:1443-1447.

    Google Scholar 

  27. Lewis EJ, Hunsicker LG, Bain RP, Rohde RD for the Collaborative Study Group. The effect of angiotensin-converting enzyme inhibition on diabetic nephropathy. N Engl J Med 1993;329:1456-1462.

    Google Scholar 

  28. Agardh C-D, Garcia-Puig J, Charbonnel B, et al. Greater reduction of urinary albumin excretion in hypertensive type II diabetic patients with incipient nephropathy by lisinopril than by nifedipine. J Hum Hypertens 1996;10:185-192.

    Google Scholar 

  29. Nielsen FS, Rossing P, Gall M-A, et al. Impact of lisonopril and atenolol on kidney function in hypertensive NIDDM subjects with diabetic nephropathy. Diabetes 1994;43: 1108-1113.

    Google Scholar 

  30. EUCLID Study Group. (EURODIAB Controlled Trial of Lisinopril in Insulin-dependent Diabetes) Randomised placebo-controlled trial of lisinopil in normotensive patients with insulin-dependent diabetes and normoalbuminuria or microalbuminuria. Lancet 1997;349:1787-1792.

    Google Scholar 

  31. Fioretto P, Frigato F, Velussi M, et al. Effects of angiotensin converting enzyme inhibitors and calcium antagonists on atrial natriuretic peptide release and action and on albumin execretion rate in hypertensive insulin-dependent diabetic patients. Am J Hypertens 1992;5:837-846.

    Google Scholar 

  32. Viberti G, Mogenson CE, Groop LC, Pauls JF for the European Microalbumuria Captopril Study Group. Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria. JAMA 1994;271:275-279.

    Google Scholar 

  33. Bakris GL, Barnhill BW, Sadler R. Treatment of arterial hypertension in diabetic humans: Importance of therapeutic selection. Kidney Int 1992;41:912-919.

    Google Scholar 

  34. Schneider M, Lerch M, Papiri M, et al. Metabolic neutrality of combined verapamil-trandolapril treatment in contrast to beta-blocker-low-dose chlorthalidone treatment in hypertensive type 2 diabetes. J Hypertens 1996;14:660-677.

    Google Scholar 

  35. Curb JD, Pressel SL, Cutler JA, et al. Effect of diureticbased antihypertensive treatment on cardiovascular disease risk in older diabetic patients with isolated systolic hypertension. JAMA 1996;276:1886-1892.

    Google Scholar 

  36. Meyer C, Nielsen FS, Sato A, et al. Beneficial effect of acute ACE inhibition on vasomotion and myocardial perfusion in type II diabetics with left ventricular hypertrophy (abstrt). Circulation 1997;96(Suppl. 1): 1-166.

    Google Scholar 

  37. Navis G, de Zeeuw D, de Jong PE. ACE-inhibitors: Panacea for progressive renal disease? Lancet 1997;349:1852-1853.

    Google Scholar 

  38. Kuusisto J, Mykkanen L, Pyorala K, Laakso M. Hyperinsulinemic microalbuminuria. A new risk indicator for coronary heart disease. Circulation 1995;91:831-837.

    Google Scholar 

  39. Paolisso G, Bambardella A, Verza M, et al. ACE inhibition improves insulin-sensitivity in aged insulin-resistant hypertensive patients. J Hum Hypertens 1992;6:175-179.

    Google Scholar 

  40. Giatras I, Lau J, Levey AS. Effect of angio-converting enyzme inhibitors on the progression of nondiabetic renal disease: A meta-analysis of randomized trials. Ann Intern Med 1997;127:337-345.

    Google Scholar 

  41. GISEN Group. (Gruppo Italiano di Studi Epidermiologici in Nefrologia). Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, non-diabetic nephropathy. Lancet 1997;349:1857-1863.

    Google Scholar 

  42. Borch-Johnsen K, Wenzel H, Viberti GC, Mogensen CE. Is screening and intervention for microalbuminuria worthwhile in patients with insulin dependent diabetes? Br Med J 1993;306:1722-1723.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ischaemic Heart Disease Research Unit of the Medical Research Council, University of Cape Town, Medical School, Observatory, Cape Town, South Africa

    Lionel H. Opie

Authors
  1. Lionel H. Opie
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Opie, L.H. Personal Viewpoint: New Developments in the Therapy of Diabetic Hypertensive Disease. The ABCD Study Adds to Strong Evidence Favoring the Prime Use of ACE Inhibitors. Cardiovasc Drugs Ther 12, 233–238 (1998). https://doi.org/10.1023/A:1007752813927

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1007752813927

Search

Navigation