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Comparison of three assays for HIV antibodies detection in urineto be applied to epidemiological setting

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Abstract

Three immune-enzymatic tests for urinary HIV antibodies were examined in order to assess their sensibility, specificity and δ value. The highest sensibility was noticed for the Seradyn test (98.8%), followed by the Wellcozyme test (98.1%) and finally the SUDS rapid test (56.8%). The resultant specificity was 98.5% for the Seradyn test, 91.3% for the Wellcozyme test and 97.3% for the SUDS test. The measurement of δ value showed a higher capability of discrimination for Seradyn test, that could be considered the most reliable for epidemiological purposes.

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Authors and Affiliations

  1. Dipartimento di Biomedicina Sperimentale Infettiva e Pubblica, Sezione di Igiene ed Epidemiologia, Università di Pisa, Pisa, Italy

    Annalaura Carducci, Beatrice Casini, Francesca Morleo & Alessia Giuntini

  2. Unità Operativa di Malattie Infettive dell'Azienda Ospedaliera Pisana, Pisa, Italy

    Marco Parenti

  3. Centro Trasfusionale dell'Ospedale Santa Chiara di Pisa, Pisa, Italy

    Rodolfo Moretti

Authors
  1. Annalaura Carducci
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  2. Beatrice Casini
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  3. Francesca Morleo
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  4. Alessia Giuntini
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  5. Marco Parenti
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  6. Rodolfo Moretti
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Carducci, A., Casini, B., Morleo, F. et al. Comparison of three assays for HIV antibodies detection in urineto be applied to epidemiological setting. Eur J Epidemiol 15, 545–548 (1999). https://doi.org/10.1023/A:1007575705141

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  • DOI: https://doi.org/10.1023/A:1007575705141

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