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Distribution of Borrelia burgdorferi sensu lato genomic groups in Europe, a review

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Abstract

The present study was designed to investigate relationships between urinary free pyridinolines (F-Pyr), serum osteocalcin (OC) and appendicular bone mineral density (BMD). Furthermore, possible correlations between such variables and putative risk factors for low bone density were also analysed. We were not able to find any relationships between biochemical markers of bone turnover and appendicular BMD or putative risk factors for osteoporosis at multivariate analysis. Multivariate analysis showed a significant decrease of BMD when age increases (p < 0.001), with menopause and time since menopause (p < 0.001), while number of pregnancies (p = 0.018) was associated with a higher value of BMD. Age, menopause and time since menopause were significantly associated with urinary excretion of F-Pyr. Indeed age was an inverse effect modifier of the relationship between urinary excretion of F-Pyr and time since menopause.

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Author notes

  1. Alfredo Colonna

    Present address: Department of Experimental Pharmacology, University of Naples ‘Federico II’, Italy

Authors and Affiliations

  1. Orthopaedic Clinic, Catanzaro Medical School, University of Reggio Calabria, Italy

    Massimo Mariconda, Oscar Marsico, Francesco Sanzo & Carlo Milano

  2. Chair of Hygiene, Catanzaro Medical School, University of Reggio Calabria, Italy

    Maria Pavia

  3. Department of Experimental and Clinical Medicine, Catanzaro Medical School, University of Reggio Calabria, Italy

    Alfredo Colonna & Carlo Mancuso

  4. Hygiene, Catanzaro Medical School, University of Reggio Calabria, Italy

    Italo F. Angelillo (Chair)

Authors
  1. Massimo Mariconda
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  2. Maria Pavia
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  4. Italo F. Angelillo
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  8. Carlo Milano
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Mariconda, M., Pavia, M., Colonna, A. et al. Distribution of Borrelia burgdorferi sensu lato genomic groups in Europe, a review. Eur J Epidemiol 13, 909–917 (1997). https://doi.org/10.1023/A:1007424507919

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