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Tuberculous pericarditis and Aids: Case reports and review

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Abstract

Pericarditis is one of the most common cardiac complications in the course of HIV disease. Opportunistic infections and neoplastic processes represent the most common etiology of pericardial disease. Pericardial tuberculosis is an uncommon condition, especially in developed countries. Two cases of tuberculous pericarditis in adult patients with AIDS occurred over a 12-month period at our clinic, which prompted a literature review of the published cases of tuberculous pericarditis in AIDS. Of note is that in the first patient pericardial effusion represented the AIDS-defining illness and was an expression of a disseminated tuberculous disease. The second patient developed a fatal pericarditis due to a multiple-drug resistant Mycobacterium tuberculosis infection.

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References

  1. Kaul S, Fishbein MC, Siegel RJ. Cardiac manifestations of acquired immune deficiency syndrome: A 1991 update. Am Heart J 1991; 122: 535–544.

    Google Scholar 

  2. Anderson DW, Virmani R. Emerging patterns of heart disease in human immunodeficiency virus infection. Hum Pathol 1990; 21: 253–259.

    Google Scholar 

  3. Raviglione MC, Narain JP, Kochi A. HIV-associated tuberculosis in developing countries: Clinical features, diagnosis, and treatment. Bull WHO 1992; 70: 515–526.

    Google Scholar 

  4. Girling DJ, Darbyshire JH, Humphries MJ, O'Mahoney SG. Extra-pulmonary tuberculosis. Br Med Bull 1988; 44: 738–756.

    Google Scholar 

  5. Medical Research Council Tuberculosis and Chest Diseases Unit. National survery of tuberculosis notifications in England and Wales in 1983: Characteristics of disease. Tubercle 1987; 68: 19–32.

    Google Scholar 

  6. Schepers GWH. Tuberculous pericarditis. Am J Cardiol 1962; 9: 248–252.

    Google Scholar 

  7. Permanyer-Miralda G, Sagristá-Sauleda J, Soler-Soler J. Primary acute pericardial disease: A prospective series of 231 consecutive patients. Am J Cardiol 1985; 56: 623–630.

    Google Scholar 

  8. Hugo-Hamman CT, Scher H, De Moor MMA. Tuberculous pericarditis in children: A review of 44 cases. Pediatr Infect Dis J 1994; 13: 13–18.

    Google Scholar 

  9. Strang JIG, Kasaza HHS, Gibson DG, Girling DJ, Nunn AJ, Fox W. Controlled trial of prednisolone as adjuvant in treatment of tuberculous contrictive pericarditis in Transkei. Lancet 1987 (ii): 1418–1422.

    Google Scholar 

  10. Strang JIG, Kasaza HHS, Gibson DG, Allen BW, Mitchison DA, Evans DJ, Girling DJ, Nunn AJ. Controlled clinical trial of complete open surgical drainage and of prednisolone in treatment of tuberculous pericardial effusion in Transkei. Lancet 1988 (ii): 759–764.

    Google Scholar 

  11. Barnes PF, Bloch AB, Davidson PT, Snider DE. Tuberculosis in patients with human immunodeficiency virus infection. N Engl J Med 1991; 324: 1644–1650.

    Google Scholar 

  12. Haas DW, Des Prez RM. Tuberculosis and acquired immunodeficiency suyndrome: A historical perspective on recent developments. Am J Med 1994; 96: 439–450.

    Google Scholar 

  13. Kinney EL, Monsuez JJ, Kitzis M, Vittecoq D. Treatment of AIDS-associated heart disease. Angiology 1989; 97: 970–976.

    Google Scholar 

  14. Elliott AM, Luo N, Tembo G, et al. Impact of HIV on tuberculosis in Zambia: A cross-sectional study. Br Med J 1990; 301: 412–415.

    Google Scholar 

  15. Elliott AM, Halwiindi B, Hayes RJ, et al. The impact of human immunodeficiency virus on presentation and diagnosis of tuberculosis in a cohort study in Zambia. J Trop Med Hyg 1993; 96: 1–11.

    Google Scholar 

  16. Cegielski JP, Ramaiya K, Lallinger GJ, Mtulia IA, Mbaga IM. Pericardial disease and human immunodeficiency virus in Dar es Salaam, Tanzania. Lancet 1990; 335: 209–212.

    Google Scholar 

  17. Taelman H, Kagame A, Batungwanyo J, et al. Pericardial effusion and HIV infection. Lancet 1990; 335: 924.

    Google Scholar 

  18. Kelly P, Burham G, Radford C. HIV seropositivity and tuberculosis in a rural Malawi hospital. Trans R Soc Trop Med Hyg 1990; 84: 725–727.

    Google Scholar 

  19. Githui W, Nunn P, Juma E, et al. Cohort study of HIV-positive and HIV-negative tuberculosis, Nairobi, Kenya: Comparison of bacteriologic results. Tuber Lung Dis 1992; 73: 203–209.

    Google Scholar 

  20. Pozniak AL, Weinberg J, Mahari M, et al. Tuberculous pericardial effusion associated with HIV infection: A sign of disseminated disease. Tuber Lung Dis 1994; 75: 297–300.

    Google Scholar 

  21. Cegielski JP, Lwakatare J, Dukes CS, et al. Tuberculous pericarditis in Tanzanian patients with and without HIV infection. Tuber Lung Dis 1994; 75: 429–434.

    Google Scholar 

  22. Tonduangu K, Longo-Mbenza B, Lutete K, Kintoki V, Izzia K, Muyembe T. Pericarditis liquidiennes au cours du syndrome d'immunodeficience acquise (SIDA): A propos de 23 cas à Kinshasa (Zaïe). Médecine d'Afrique Noire 1995; 42: 673–676.

    Google Scholar 

  23. Pitchenik AE, Cole C, Russel BW, Fischl MA, Spira TJ, Snider DE. Tuberculosis, atypical mycobacteriosis, and the acquired immunodeficiency syndrome among Haitian and non-Haitian patients in south Florida. Ann Intern Med 1984; 101: 641–645.

    Google Scholar 

  24. Sunderam, McDonald RJ, Maniatis T, Oleske J, Kapila R, Reichman LB. Tuberculosis as a manifestation of the acquired immunodeficiency syndrome (AIDS). JAMA 1986; 256: 362–366.

    Google Scholar 

  25. D'Cruz IA, Sengupta EE, Abrahams C, Reddy HK, Turlapati RV. Cardiac involvement, including tuberculous pericardial effusion, complicating acquired immune deficiency syndrome. Am Heart J 1986; 112: 1100–1102.

    Google Scholar 

  26. Dalli E, Quesada A, Juan G, Navarro R, Payá R, Tormo V. Tuberculous pericarditis as the first manifestation of acquired immunodeficiency syndrome. Am Heart J 1987; 114: 905–906.

    Google Scholar 

  27. Monsuez JJ, Kinney EL, Vittecoq D, et al. Comparison among acquired immune deficiency syndrome patients with and without clinical evidence of cardiac disease. Am J Cardiol 1988; 62: 1311–1313.

    Google Scholar 

  28. De Miguel J, Pedreira JD, Campos V, Perez Gomez A, Porto JAL, Canalejo J. Tuberculous pericarditis and AIDS. Chest 1990; 5: 1273.

    Google Scholar 

  29. Reynolds MM, Hecht SR, Berger M, Kolokathis A, Horowitz SF. Large pericardial effusions in the acquired immunodeficiency syndrome. Chest 1992; 102: 1746–1747.

    Google Scholar 

  30. Horn DL, Hewlett D, Alfalla C, Peterson S. Fatal hospital-acquired multidrug-resistant tuberculous pericarditis in two patients with AIDS. NEJM 1992; 327: 1816–1817.

    Google Scholar 

  31. Pedro-Botet J, Auguet T, Coll J, Pons S, Rubiés-Prat J. Tuberculous pericarditis as the first manifestation of AIDS. Infection 1993; 21: 224–335.

    Google Scholar 

  32. Bertolaccini P, Chimenti M, Bianchi S, Manfredini G, Barattini G, Maneschi A. Gallium-67 scintigraphy in an AIDS patient presenting tuberculous pericarditis. J Nucl Biol Med 1993; 37: 245.

    Google Scholar 

  33. De Miguel J, Pedreir JD, Pericarditis tuberculosa. Aspectos clinicos en pacientes con y sin SIDA. Rev Clin Esp 1994; 194: 139–140.

    Google Scholar 

  34. Ewig S, Fehske W, Omran H, Rockstroh JK, Luderitz B. Kardiale manifestationen bei fortgeshrittener HIV-infektion. Dtsch Med Wochenschr 1994; 119: 683–689.

    Google Scholar 

  35. Serrano-Heranz R, Camino A, Vilacosta I, Lopez-Castellanos A, Roca V. Tuberculous cardiac tamponade and AIDS. Eur Heart J 1995; 16: 430–432.

    Google Scholar 

  36. Suresh JA, Haas DW. Tuberculous pericarditis in an HIV-infected patient. Scand J Infect Dis 1995; 27: 411–413.

    Google Scholar 

  37. Schmidt U, Rebarber IF. Tuberculous pericarditis identified with gallium-67 and indium-111 leukocyte imaging. Clin Nucl Med 1994; 19: 146–147.

    Google Scholar 

  38. Senderovitz T, Viskum K. Kortikosteroid som adjuverende behandling ved tuberkulose. Ugeskr Laeger 1994; 156: 5268–5272.

    Google Scholar 

  39. Elliott AM, Halwiindi B, Bagshawe A, et al. Use of prednisolone in the treatment of HIV-positive individuals. Q J Med 1992; (New series 85) 307–308; 855–860.

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Mastroianni, A., Coronado, O. & Chiodo, F. Tuberculous pericarditis and Aids: Case reports and review. Eur J Epidemiol 13, 755–759 (1997). https://doi.org/10.1023/A:1007313902175

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