Abstract
To compare the anti-inflammatory effectiveness of corticotherapy and non-steroid anti-inflammatory drugs (NSAID), we examined 126 infertile men with infectious aetiology. Seventy-seven patients were on corticotherapy and antibiotherapy (thirty-eight patients on high-dose and thirty-nine patients on low-dose corticotherapy). Forty-nine patients had antibiotherapy and NSAID. According to our results in both the high- and low-dose groups sperm motility significantly improved, but in the high dose group more side effects were reported. In order to overcome the effects of infections on male infertility, we prefer corticotherapy instead of NSAID because it is more effective than NSAID.
Similar content being viewed by others
References
Pryor, J. P., Hendry, W. F.: Ejaculatory duct obstructions in subfertile males: Analysis of 87 patients. Fertil. Steril., 56, 715 (1991).
Uehling, D. T.: Low-dose cortisone for male infertility. Fertil. Steril., 29, 220 (1978).
Kaufman, D. G., Nagler, H. M.: Specific nonsurgical therapy in male infertility. Urol., Clin. North Am., 49, 491 (1987).
Harrison, R. F., Blades, M., DeLouvois, J.: Doxycycline treatment and human infertility. Lancet, 1, 605 (1975).
Moskowitz, M. O., Mellinger, B. B.: Sexually transmitted diseases and their relation to male infertility. Urol. Clin. North Am., 19, 35 (1992).
Berger, R. E., Alexander, E. R., Harnisch, J. P.: Etiology, manifestations and therapy of acute epididymis: Prospective study of 50 cases. J. Urol., 121, 750 (1979).
Maruyama, D. K., Hale, R. W., Rogers, B. J.: Effects of white blood cells on the in vitro penetration of zona-free hamster eggs by human spermatozoa. J. Androl., 6, 127 (1985).
Berger, R. E., Alexander, E. R., Monda, G. D.: Chlamydia trachomatis as a cause of acute “idiopathic” epididymitis. N. Engl. J. Med., 298, 301 (1978).
Wolff, H., Politch, J. A., Martinez, A.: Leukocytospermia is associated with poor semen quality. Fertil. Steril. 53, 528 (1990).
Megroy, E., Zuckerman, J., Shoham, A: Infections and male infertility. Obstet. Gynecol. Surv., 42, 283 (1987).
Comhare, E., Verschdeagen, G., Vermeulen, L.: Diagnosis of accessory gland infection and its possible role in male infertility. Int. J. Androl., 3, 32 (1980).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Altay, B., Girgin, C. & Çikili, N. Comparing the Anti-Inflammatory Effects of Corticotherapy and Non-steroid Anti-Inflammatory Drugs in Infertile Patients with Infectious Aetiology. Int Urol Nephrol 31, 101–106 (1999). https://doi.org/10.1023/A:1007184125900
Issue Date:
DOI: https://doi.org/10.1023/A:1007184125900