Skip to main content

Ruthenium(II) complexes containing bidentate Schiff bases and their antifungal activity

Abstract

The reactions of ruthenium(II) complexes, [RuHCl(CO)(PPh3)2(B)] [B = PPh3, pyridine (py) or piperidine (pip)], with bidentate Schiff base ligands derived by condensing salicylaldehyde with aniline, o-, m- or p-toluidine have been carried out. The products were characterised by analytical, i.r., electronic, 1H-n.m.r. and 31P-n.m.r. spectral studies and are formulated as [RuCl(CO)(L)(PPh3)(B)] (L = Schiff base anion; B = PPh3, py or pip). An octahedral structure has been tentatively proposed for the new complexes. The Schiff bases and the new complexes were tested in vitro to evaluate their activity against the fungus Aspergillus flavus.

This is a preview of subscription content, access via your institution.

References

  1. M.M.T. Khan, S.B. Halligudi, S. Shukla and Z.A. Shaik, J. Mol. Catal., 57, 301 (1990).

    Google Scholar 

  2. M.M.T. Khan, S.B. Halligudi and N.S. Rao, J. Mol. Catal., 63, 137 (1990).

    Google Scholar 

  3. Y. Aoyama, T. Fujisawa, T. Walanav, H. Toi and H. Ogashi, J. Am. Chem. Soc., 108, 943 (1986).

    Google Scholar 

  4. E. Kimura, R. Machida and M. Kochima, J. Am. Chem. Soc., 106, 5497 (1984).

    Google Scholar 

  5. P.K. Bhattacharya, Proc. Ind. Acad. Sci., (Chem. Sci.), 102, 247 (1990).

    Google Scholar 

  6. R.S. Brown, M. Zamakani and J.L. Sho, J. Am. Chem. Soc., 106, 5222 (1984).

    Google Scholar 

  7. H.A. Cyba, Chem. Abstr., 69, 6364 (1968).

    Google Scholar 

  8. T. Snamt and S. Umezari, Bull. Chem. Soc. Jpn., 29, 975 (1956).

    Google Scholar 

  9. M.M.T. Khan and Z.A. Shaikh, Ind. J. Chem., 31A, 191 (1992).

    Google Scholar 

  10. L.W. Hung and C.C. Ming, Inorg. Chem., 28, 4619 (1989).

    Google Scholar 

  11. J. Halpern, B.R. James and A.L.W. Kemp, J. Am. Chem. Soc., 88, 5142 (1966).

    Google Scholar 

  12. K.S. Murray, A.M. Van den Bergen and B.O. West, Aust. J. Chem., 31, 203 (1978).

    Google Scholar 

  13. A.I. Vogel, Textbook of Practical Organic Chemistry, Longman, London, 1989.

  14. N. Ahmad, J.J. Levison, S.D. Robinson and M.F. Uttley, Inorg. Synth., 15, 48 (1974).

    Google Scholar 

  15. S. Gopinathan, I.R. Unny, S.S. Deshpande and C. Gopinathan, Ind. J. Chem., 25A, 1015 (1986).

    Google Scholar 

  16. B. Khera, A.K. Sharma and N.K. Kaushik, Polyhedron, 2, 1177 (1983).

    Google Scholar 

  17. J.M. Vincent, Nature, 189, 850 (1947).

    Google Scholar 

  18. J. Uttamchandani and R.N. Kapoor, Transition Met. Chem., 3, 282 (1978).

    Google Scholar 

  19. L.J. Boucher, J. Inorg. Nucl. Chem., 36, 531 (1974).

    Google Scholar 

  20. R. Ramesh, P.K. Suganthy and K. Natarajan, Synth. React. Inorg. Met.-Org. Chem., 26, 47 (1996).

    Google Scholar 

  21. K. Nakamoto, Infrared Spectra of Inorganic and Coordination Compounds, 2nd edit., Wiley, New York, 1972.

    Google Scholar 

  22. G. Muthusamy and K. Natarajan, Ind. J. Chem., 30A, 626 (1991).

    Google Scholar 

  23. G. Muthusamy, R. Ramesh and K. Natarajan, Synth. React. Inorg. Met.-Org. Chem., 24, 545 (1994).

    Google Scholar 

  24. M. Plytzanopoubs, E. Pnematikakis, N. Hajiliedis and D. Katakis, J. Inorg. Nucl. Chem., 39, 965 (1977).

    Google Scholar 

  25. N. Jayakumar, T. Banumathi, M.V. Chandini Devi and K. Natarajan, Ind. J. Chem., 29A, 885 (1990).

    Google Scholar 

  26. A.B.P. Lever, Inorganic Electronic Spectroscopy, 2nd edit., Else-vier, New York, 1984.

    Google Scholar 

  27. G. Muthusamy and K. Natarajan, Ind. J. Chem., 34A, 490 (1995).

    Google Scholar 

  28. N. Dharmaraj and K. Natarajan, Ind. J. Chem., 33A, 785 (1994).

    Google Scholar 

  29. K. Natarajan, R.K. Poddar and U. Agarwala, J. Inorg. Nucl. Chem., 39, 431 (1977).

    Google Scholar 

  30. B.G. Tweedy, Phytopathology, 55, 910 (1964).

    Google Scholar 

  31. S.C. Singh Jadon, N. Gupta and R.V. Singh, Ind. J. Chem., 34A, 733 (1995).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Dharmaraj, N., Viswanathamurthi, P. & Natarajan, K. Ruthenium(II) complexes containing bidentate Schiff bases and their antifungal activity. Transition Metal Chemistry 26, 105–109 (2001). https://doi.org/10.1023/A:1007132408648

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1007132408648

Keywords

  • Physical Chemistry
  • Inorganic Chemistry
  • Pyridine
  • Aspergillus
  • Aniline