Abstract
Complex formation equilibria involving [Pd(bpy)(H2O)2]2+ (bpy = 2,2′-bipyridine) and the cyclobutanedicarboxylate ligand (cbdca), ethylenediamine and DNA have been investigated. Mixed ligand complexes of [Pd(bpy)(cbdca)] with inosine, inosine-5′-monophosphate (5′-IMP), uracil, uridine and adenine have been studied. The results show ring opening of the cbdca and monodentate chelation of the DNA components. Stoichiometries and stability constants for the complexes were determined at 25 °C and at constant 0.1 M ionic strength (adjusted using NaNO3). The coordination sites were found to be pH-dependent. The [Pd(bpy)Cl2], [Pd(bpy)(cbdca)] and [Pd(bpy)(inosine)](NO3) complexes were isolated.
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Shehata, M.R. Mixed ligand complexes of diaquo (2,2′-bipyridine)palladium(II) with cyclobutane-1,1-dicarboxylic acid and DNA constituents. Transition Metal Chemistry 26, 198–204 (2001). https://doi.org/10.1023/A:1007114128293
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DOI: https://doi.org/10.1023/A:1007114128293