Abstract
We report a fatal case of fungal (candidal) endocarditis of the tricuspid valve with clinico-pathologically interesting findings following and associated with candidal pneumonia during long-term central venous catheterization (CVC) for intravenous therapy and long-term treatment with antibiotics for bacterial and fungal infection in a patient with a history of alcohol abuse. We review the literature on fungal cardiac infection related to long-term catheterization and alcohol abuse, and discuss the pathogenesis.
Similar content being viewed by others
References
Aubaniac P. L. injection intraveineuse sousclaviculaire: Advantages et technique. Presse Medicale 1952; 60: 1456.
Walsh TJ, Hutchins GM. Aspergillus mural endocarditis. Am J Clin Pathol 1979; 71: 640–644.
Cox JN, di Dio F, Pizzolato G-P, Lerch R, Pochon N. Aspergillus endocarditis and myocarditis in a patient with the acquired immunodeficiency syndrome (AIDS). A review of the literature. Virchows Archiv A Pathol Anat 1990; 417: 255–259.
Henochowicz S, Musafa M, Lawrinson WE, Pistole M, Lindsay J. Cardiac aspergillosis in acquired immune deficiency syndrome. Am J Cardio 1989; 55: 1239–1240.
Armstrong D. Opportunistic infections in the acquired immune deficiency syndrome. Semin Oncol 1987; 14: 40–47.
Hogevik H and Alestig K. Fungal endocarditis - A report on seven cases and a brief review. Infection 1996; 24: 17–21.
Baddour LM. Long-term suppressive therapy for fungal endocarditis. Clin Infect Dis 1996; 23: 1338–1340.
Gilbert HM, Peters ED, Lang SJ, Hartman BJ. Successful treatment of fungal prosthetic valve endocarditis: case report and review. Clin Infect Dis 1996; 22: 348–354.
Mansur SJ, Safi J Jr, Markus MRP, Aiello VD, Grinberg M, Pomerantzeff PMA. Late failure of surgical treatment for bioprosthetic valve endocarditis due to Candida tropicalis. Clin Infec Dis 1996; 22: 380–381.
Muchreke DD, Lytle BW, Cosgrove DM III. Surgical and long-term antifungal therapy for fungal prosthetic valve endocarditis. Ann Thorac Surg 1995; 60: 538–543.
Lozano P, Flores D, Blanes I, Rimbau E, Corominas C, Julia J, Garcia DLTA. Acute lower limb ischemia complicating endocarditis due to Candida parapsilosis in a drug user. Ann Vasc Surg 1994; 8: 591–594.
Jerrells TR. Immunodeficiency associated with ethanol abuse. Adv Exp Med Biol 1991; 288: 229–236.
Abe F, Tateyama M, Shibuya H, Azumi N, Omura Y. Disseminated fungal infection. A review of 20 autopsy cases. Acta Pathol Jpn 1984; 34: 1201–1208.
Becker AE, Becker MJ, Martin FH, et al. Bland thrombosis and infection in relation to intracardiac catheter. Circulation 1972; 46: 200–203.
Atkinson JB, Conner DH, Robinowitz M, McAllister HA, Virmani P. Cardiac fungal infections: Review of autopsy findings in 60 patients. Hum Pathol 1984; 15: 935–942.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ohmori, T., Iwakawa, K., Matsumoto, Y. et al. A fatal case of fungal endocarditis of the tricuspid valve associated with long-term venous catheterization and treatment with antibiotics in a patient with a history of alcohol abuse. Mycopathologia 139, 123–128 (1997). https://doi.org/10.1023/A:1006877212491
Issue Date:
DOI: https://doi.org/10.1023/A:1006877212491