Abstract
Speciation analysis of trace elements is the identification and/or measurement of the quantities of one or more individual chemical species in a sample. The general procedure starts with the separation of the species followed by the measurement of trace elements in the different fractions. The identification of the species may be done by UV-detection, mass spectrometry or other techniques. For the development of the methodology, and for in-vivo and in-vitro studies radiotracers are ideally suited. In speciation analysis of trace elements in biological fluids and tissues the search goes on for small inorganic and organometallic compounds, and for metal-protein complexes.
Similar content being viewed by others
References
R. Cornelis, Analyst, 11 (1992) 583.
R. Cornelis, F. Borguet, J. De Kimpe, Anal. Chim. Acta, 283 (1993) 183.
R. Cornelis, Annals Clin. Lab. Sci., 26 (1996) 252.
R. Cornelis, J. De Kimpe, J. Anal. Atom. Spectrom., 9 (1994) 945.
D. M. Templeton, Fresenius J. Anal. Chem., 363 (1999) 505.
R. Cornelis, J. De Kimpe, X. Zhang, Spectrochim. Acta, B53 (1998) 187.
F. Borguet, R. Cornelis, J. Delanghe, M-C. Lambert, N. Lameire, Clin. Chim. Acta, 238 (1995) 71.
J. De Kimpe, R. Cornelis, L. Mees, R. Vanholder, Fund. Appl. Toxicol., 34 (1996) 240.
J. De Kimpe, R. Cornelis, L. Wittevrongel, R. Vanholder, J. Trace Elements Med. Biol., 12 (1998) 193.
J. De Kimpe, R. Cornelis, L. Wittevrongel, R. Vanholder, J. Trace Elements Med. Biol., 13 (1999) 1.
S. Lustig, J. De Kimpe, R. Cornelis, P. Schramel, Fresenius J. Anal. Chem., 363 (1999) 484.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Cornelis, R. Unique Possibilities Offered by Radio-Tracers for Speciation Analysis of Trace Elements in Biological Fluids and Tissues. Journal of Radioanalytical and Nuclear Chemistry 244, 255–257 (2000). https://doi.org/10.1023/A:1006773828316
Issue Date:
DOI: https://doi.org/10.1023/A:1006773828316